Avat Arman Taherpour | Medicinal Chemistry | Best Researcher Award

Posted on by sciencefather

Prof Dr. Avat Arman Taherpour | Medicinal Chemistry | Best Researcher Award

Professor at Al-Balqa Applied University, Jordan

Avat Arman Taherpour is a distinguished Professor of Organic Chemistry at Razi University, Kermanshah, Iran, and a respected researcher at the Medical Biology Research Center, Kermanshah University of Medical Sciences. With a Ph.D. in Organic Chemistry from Islamic Azad University, Tehran, and post-doctoral experience at The University of Queensland, Australia, under Professor Curt Wentrup, he specializes in computational chemistry, organic synthesis, and nano-chemistry. Avat’s research focuses on applying quantum mechanical methods to study molecular structures and interactions, essential for advancing medicinal chemistry and nano-materials. He has authored numerous publications and holds international recognition, listed among the top 2% researchers worldwide. Beyond academia, Avat has held significant managerial roles, including President of the Elites Foundation in Kermanshah Province, Iran, emphasizing his leadership in fostering scientific excellence and industry collaboration. His contributions continue to shape the fields of theoretical chemistry and organic synthesis globally.

Professional Profiles:

šŸŽ“ Education

Avat Arman Taherpour pursued his academic journey with a strong foundation in chemistry, earning a B.Sc. in Applied Chemistry from Islamic Azad University, Tehran, Iran in 1990. He continued his studies with an M.Sc. in Organic Chemistry from the same institution in 1992, further deepening his expertise in chemical sciences. Avat Arman Taherpour completed his academic trajectory with a Ph.D. in Organic Chemistry from the Islamic Azad University Science and Research Branch, Tehran, Iran, in 1998. His educational background provided him with a robust theoretical framework and practical skills essential for his subsequent research and professional endeavors in the field of organic chemistry.

Ā Professional Experience

Avat Arman Taherpour is a distinguished Professor of Organic Chemistry at Razi University, Kermanshah, Iran, where he also serves as an invited researcher at the Medical Biology Research Center, Kermanshah University of Medical Sciences. With a robust academic background, including a Ph.D. in Organic Chemistry and post-doctoral research at The University of Queensland, Australia, he specializes in Organic and Medicinal Chemistry, Quantum Mechanical and Computational Chemistry, and Nano-Chemistry. Avat has held significant administrative roles, such as President of the Elites Foundation for Kermanshah Province and Head of the Nano-Chemistry Department at Razi University. His career highlights include fostering industry-academia partnerships and contributing extensively to the advancement of scientific research and education in Iran.

Research Interest

Avat Arman Taherpour’s research interests encompass a wide array of fields within chemistry, focusing primarily on Organic and Medicinal Chemistry. His expertise extends to Quantum Mechanical and Computational Chemistry, Molecular Modeling, Theoretical Chemistry, and Physical Organic Chemistry. He is deeply engaged in Spectroscopic Studies of Organic Compounds and Nano-Chemistry, exploring innovative applications and theoretical frameworks. Avat’s research aims to bridge theoretical insights with practical applications, emphasizing the role of computational tools in enhancing experimental outcomes and understanding molecular interactions. His work underscores the importance of advancing chemical sciences through interdisciplinary approaches, particularly in areas like biochemistry, nano-systems, and medicinal chemistry, thereby contributing to both theoretical advancements and practical innovations in the field.

Award and Honors

Avat Arman Taherpour has been recognized internationally for his contributions to the field of chemistry, notably being listed among the top 2% researchers worldwide in all fields in 2019, 2020, and 2021. This prestigious recognition underscores his significant impact and scholarly contributions to scientific research. His achievements reflect his dedication to advancing knowledge in Organic and Medicinal Chemistry, Quantum Mechanical and Computational Chemistry, and Nano-Chemistry. Avat’s commitment to excellence in research and his innovative approaches have earned him acclaim within the global scientific community, highlighting his influential role in pushing the boundaries of chemical sciences

Research Skills

Avat Arman Taherpour is a distinguished researcher with a profound expertise in various domains of chemistry. His research skills encompass computational chemistry, where he applies advanced quantum mechanical methods to explore molecular structures and interactions, particularly in organic and medicinal chemistry. He is adept at organic synthesis, having designed and synthesized intricate compounds pivotal for drug development. Utilizing spectroscopic techniques such as NMR, IR, and UV spectroscopy, Avat characterizes organic and medicinal compounds with precision, elucidating their structural properties. His proficiency extends to nano-chemistry, where he investigates nano-scale materials for diverse applications in chemical sciences. Additionally, Avat’s knowledge in physical organic chemistry enables him to delve into reaction mechanisms and the physical properties of organic compounds, essential for enhancing synthetic strategies and understanding chemical behaviors. His comprehensive skill set integrates theoretical insights with practical applications, positioning him as a leading figure in advancing innovative research at the intersection of chemistry disciplines.

Publications

  1. Molecular modelling of fullerene C60 functionalized by nitric oxide for use in biological environment
    • Authors: Moztarzadeh, O., Jamshidi, M., Taherpour, A.A., Babuska, V.
    • Year: 2024
    • Journal: Scientific Reports
    • Volume: 14(1)
    • Pages: 2565
  2. Nitrile Imine Cyclizations and Rearrangements: N-Phenyl-C-styrylnitrile Imine and N-Phenyl-C-phenylethynylnitrile Imine
    • Authors: Miri, M., Taherpour, A.A., Wentrup, C.
    • Year: 2024
    • Journal: Journal of Organic Chemistry
    • Volume: 89(13)
    • Pages: 9360ā€“9370
  3. Modeling of an efficient donor-Ļ€-acceptor-Ļ€ organic solar cell: a first principle study of a holeā€“electron process by DFT and TD-DFT study
    • Authors: Hassani Daramroudi, A., Taherpour, A.A., Jamshidi, M.
    • Year: 2024
    • Journal: Journal of the Iranian Chemical Society
    • Volume: 21(5)
    • Pages: 1353ā€“1368
  4. Ni0.5Co0.5WO4@f-MWCNTs/GO nanocomposite with improved supercapattery activity as the electrode for asymmetric supercapacitor device
    • Authors: Abdolahi, B., Gholivand, M.B., Shamsipur, M., Mirzaei, M., Daramroudi, A.H., Taherpour, A.A.
    • Year: 2023
    • Journal: Journal of Energy Storage
    • Volume: 73
    • Pages: 109181
    • Citations: 9
  5. Experimental and computational investigation of multi-walled carbon nanotubes decorated by Coā€“Niā€“Se@MoSe2 coreā€“shell as a sustainable counter electrode for dye-sensitized solar cells
    • Authors: Norouzibazaz, M., Gholivand, M.B., Taherpour, A.A., Mirzaei, M.
    • Year: 2023
    • Journal: Materials Today Energy
    • Volume: 38
    • Pages: 101447
    • Citations: 5
  6. Corrigendum to: Synthesis and Application of Nano Vanadium-Oxo Pyridiniumporphyrazinato Sulfonic Acid for Synthesizing Pyrazole and Dihydropyrano [2,3] pyrazole Derivatives
    • Authors: Moeinimehr, M., Safaiee, M., Zolfigol, M.A., Taherpour, A.A.
    • Year: 2023
    • Journal: ChemistrySelect
    • Volume: 8(16)
    • Pages: e202204422
  7. Zwitterionic hydrogen-bonded organic framework (ZHOF): a metal-free water oxidation proton relay in alkaline and neutral media
    • Authors: Azizi, R., Shamsipur, M., Taherpour, A., Pashabadi, A.
    • Year: 2023
    • Journal: Journal of Materials Chemistry A
    • Volume: 11(3)
    • Pages: 1491ā€“1502
    • Citations: 7
  8. Catalytic synergism in Mn-heterostructured molybdenum oxysulfide hybridized with transition metal phosphides: A robust amorphous water oxidation catalyst
    • Authors: Ahanjan, K., Shamsipur, M., Taherpour, A., Pashabadi, A.
    • Year: 2022
    • Journal: Electrochimica Acta
    • Volume: 433
    • Pages: 141249
    • Citations: 4
  9. An ideal ratiometric fluorescent probe provided by the surface modification of carbon dots for the determination of Pb2+
    • Authors: Paydar, S., Feizi, F., Shamsipur, M., Taherpour, A.A., Jamshidi, M.
    • Year: 2022
    • Journal: Sensors and Actuators B: Chemical
    • Volume: 369
    • Pages: 132243
    • Citations: 23
  10. Retraction: Experimental and theoretical studies of the nanostructured {Fe3O4@SiO2@(CH2)3Im}C(CN)3 catalyst for 2-amino-3-cyanopyridine preparation via an anomeric based oxidation
    • Authors: Zolfigol, M.A., Kiafar, M., Yarie, M., Taherpour, A., Saeidi-Rad, M.
    • Year: 2022
    • Journal: RSC Advances
    • Volume: 12(42)
    • Pages: 27114

 

 

Bijo Mathew | Medicinal Chemistry | Best Researcher Award

Posted on by sciencefather

Prof Dr. Bijo Mathew | Medicinal Chemistry | Best Researcher Award

Professor at Amrita School of Pharmacy India.

Prof. Dr. Bijo Mathew is a distinguished academic in pharmaceutical sciences, currently serving as a Professor at Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, Kochi. With a robust background in molecular docking and drug design using AutoDock 4.2, Biovia, and Glide, he contributes significantly as Section Editor for Coronaviruses (BenthamScience) and Editorial Member for several prestigious journals. Dr. Mathew’s teaching career spans from Assistant Professor to his current role, imparting knowledge across various institutions in India. He is a sought-after speaker, delivering talks internationally and nationally on drug design and medicinal chemistry. Recognized as one of the Top 2% Scientists by Stanford, he has received multiple awards including the Amrita Publication Research Award and Best International Collaborator Award. Dr. Mathew holds patents for compositions addressing neurological disorders, underscoring his commitment to advancing pharmaceutical research and education.

Professional Profiles:

šŸŽ“ Education

Prof. Dr. Bijo Mathew boasts a distinguished academic journey in pharmaceutical sciences, culminating in a Ph.D. from Jawaharlal Nehru Technological University, Hyderabad, India, specializing in Pharmaceutical Science. Prior to his doctoral studies, he completed his Master’s in Pharmaceutical Chemistry and Bachelor’s in Pharmacy at The Tamilnadu Dr. M.G.R. Medical University, Chennai, and his pre-degree at Mahatma Gandhi University, Kottayam, India. His doctoral research under the guidance of Dr. A. Jerad Suresh focused on the synthesis, characterization, and pharmacological evaluation of heterocyclic derivatives, contributing significantly to the field. Prof. Mathew’s academic journey is marked by a commitment to advancing pharmaceutical knowledge, evident in his extensive expertise across various domains of pharmaceutical research, including molecular docking, dynamics, and pharmacophore mapping. His educational foundation and research acumen continue to drive innovative contributions in drug discovery and development, positioning him as a prominent figure in academia and pharmaceutical research.

Area of Interest and Expertise

Prof. Dr. Bijo Mathew’s research interests encompass a diverse array of fields within pharmaceutical chemistry and drug discovery. His expertise spans the chemistry and biological exploration of various classes of compounds such as chalcones and isatins. He is involved in the synthesis and pharmacological evaluation of heterocyclic nuclei including benzimidazole, thiadiazole, pyrimidine, furan, pyrazoline, and thiazole derivatives, focusing on their potential as CNS depressants, anticonvulsants, anticancer agents, antioxidants, and neuroprotective compounds. Dr. Mathew specializes in designing inhibitors for key enzymes like MAO, AChE, BACE1, and Hsp90, utilizing techniques such as monowave-assisted synthesis and structural elucidation through IR, NMR, and MASS spectroscopy. His research also extends to molecular docking, dynamics, pharmacophore mapping, and 3D-QSAR studies, as well as the isolation and computational analysis of natural secondary metabolites from medicinal plants.

Expertise in Software:

  • AutoDock 4.2, Biovia, Glide

Editorial Contributions:

  • Section Editor for Coronaviruses (BenthamScience)
  • Editorial Member for Brain Sciences (MDPI), Combinatorial Chemistry & High Throughput Screening (Bentham Science), Molecules (MDPI), Current Topics in Medicinal Chemistry (Bentham Science), Current Drug Targets (Bentham Science)

Teaching Experience:

  • Professor at Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, Kochi, India, since April 2022
  • Associate Professor and Assistant Professor at various institutions in India prior to current position

Invited Talks:

  • Presented internationally and nationally on topics related to drug design, molecular docking, and medicinal chemistry.

Awards and Recognition:

  • Recognized with multiple awards including Top 2% Scientists from Stanford, Amrita Publication Research Award, Best International Collaborator Award, Chancellorā€™s Publication Award, Publication Merit Award, and Best Resource Person Award at National College of Pharmacy.

Patents:

  • Granted patents on compositions for neurological disorders and therapeutic agents.

Publications

  1. Elucidating molecular mechanism and chemical space of chalcones through biological networks and machine learning approaches
    • Authors: Manaithiya, A., Bhowmik, R., Acharjee, S., Parkkila, S., Aspatwar, A., Mathew, B.
    • Year: 2024
    • Citations: 0
  2. Machine learning driven web-based app platform for the discovery of monoamine oxidase B inhibitors
    • Authors: Kumar, S., Bhowmik, R., Oh, J.M., Kim, H., Mathew, B.
    • Year: 2024
    • Citations: 3
  3. Development of morpholine ring-bearing halogenated Ī±,Ī²-unsaturated ketones as selective monoamine oxidase-B inhibitors
    • Authors: Lee, J., Parmbil, S.K., Pandit, N.K., Kim, H., Mathew, B.
    • Year: 2024
    • Citations: 0
  4. Isatin-tethered halogen-containing acylhydrazone derivatives as monoamine oxidase inhibitor with neuroprotective effect
    • Authors: Kumar, S., Oh, J.M., Prabhakaran, P., Kim, H., Mathew, B.
    • Year: 2024
    • Citations: 3
  5. MzDOCK: A free ready-to-use GUI-based pipeline for molecular docking simulations
    • Authors: Kabier, M., Gambacorta, N., Trisciuzzi, D., Nicolotti, O., Mathew, B.
    • Year: 2024
    • Citations: 0
  6. Design and Synthesis of the Linezolid Bioisosteres to Resolve the Serotonergic Toxicity Associated with Linezolid
    • Authors: Girase, R.T., Ahmad, I., Oh, J.M., Kim, H., Patel, H.M., Mathew, B.
    • Year: 2024
    • Citations: 0
  7. MAO-B Inhibitor (2E)-3-(4-Bromophenyl)-1-(1H-indol-3-yl) prop-2-en-1-one as a Neuroprotective Agent Against Alzheimerā€™s Disease
    • Authors: Sasidharan, R., Mohanan, R., Kukreti, N., Manju, S.L., Mathew, B.
    • Year: 2024
    • Citations: 0
  8. Correction to: Targeting cellular batteries for the therapy of neurological diseases (Environmental Science and Pollution Research)
    • Authors: Arora, A., Behl, T., Sehgal, A., Mathew, B., Bungau, S.
    • Year: 2024
    • Citations: 0
  9. Chalcones with N-Methylpiperazine Moiety: Synthesis, Monoamine Oxidase Inhibition, Neuroprotective Effect and Computer Simulation Study
    • Authors: Jayan, J., Trisciuzzi, D., Benny, F., Nicolotti, O., Mathew, B.
    • Year: 2024
    • Citations: 0
  10. A structure-based approach to explore novel COX-2 inhibitors using pharmacophore modelling, 3D-QSAR analysis, virtual screening and dynamics simulation study
    • Authors: Krishnendu, P.R., Benny, S., Kumar, S., Zachariah, S.M., Mathew, B.
    • Year: 2024
    • Citations: 3