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Prof Dr. Bijo Mathew | Medicinal Chemistry | Best Researcher Award

Professor at Amrita School of Pharmacy India.

Prof. Dr. Bijo Mathew is a distinguished academic in pharmaceutical sciences, currently serving as a Professor at Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, Kochi. With a robust background in molecular docking and drug design using AutoDock 4.2, Biovia, and Glide, he contributes significantly as Section Editor for Coronaviruses (BenthamScience) and Editorial Member for several prestigious journals. Dr. Mathew’s teaching career spans from Assistant Professor to his current role, imparting knowledge across various institutions in India. He is a sought-after speaker, delivering talks internationally and nationally on drug design and medicinal chemistry. Recognized as one of the Top 2% Scientists by Stanford, he has received multiple awards including the Amrita Publication Research Award and Best International Collaborator Award. Dr. Mathew holds patents for compositions addressing neurological disorders, underscoring his commitment to advancing pharmaceutical research and education.

Professional Profiles:

🎓 Education

Prof. Dr. Bijo Mathew boasts a distinguished academic journey in pharmaceutical sciences, culminating in a Ph.D. from Jawaharlal Nehru Technological University, Hyderabad, India, specializing in Pharmaceutical Science. Prior to his doctoral studies, he completed his Master’s in Pharmaceutical Chemistry and Bachelor’s in Pharmacy at The Tamilnadu Dr. M.G.R. Medical University, Chennai, and his pre-degree at Mahatma Gandhi University, Kottayam, India. His doctoral research under the guidance of Dr. A. Jerad Suresh focused on the synthesis, characterization, and pharmacological evaluation of heterocyclic derivatives, contributing significantly to the field. Prof. Mathew’s academic journey is marked by a commitment to advancing pharmaceutical knowledge, evident in his extensive expertise across various domains of pharmaceutical research, including molecular docking, dynamics, and pharmacophore mapping. His educational foundation and research acumen continue to drive innovative contributions in drug discovery and development, positioning him as a prominent figure in academia and pharmaceutical research.

Area of Interest and Expertise

Prof. Dr. Bijo Mathew’s research interests encompass a diverse array of fields within pharmaceutical chemistry and drug discovery. His expertise spans the chemistry and biological exploration of various classes of compounds such as chalcones and isatins. He is involved in the synthesis and pharmacological evaluation of heterocyclic nuclei including benzimidazole, thiadiazole, pyrimidine, furan, pyrazoline, and thiazole derivatives, focusing on their potential as CNS depressants, anticonvulsants, anticancer agents, antioxidants, and neuroprotective compounds. Dr. Mathew specializes in designing inhibitors for key enzymes like MAO, AChE, BACE1, and Hsp90, utilizing techniques such as monowave-assisted synthesis and structural elucidation through IR, NMR, and MASS spectroscopy. His research also extends to molecular docking, dynamics, pharmacophore mapping, and 3D-QSAR studies, as well as the isolation and computational analysis of natural secondary metabolites from medicinal plants.

Expertise in Software:

  • AutoDock 4.2, Biovia, Glide

Editorial Contributions:

  • Section Editor for Coronaviruses (BenthamScience)
  • Editorial Member for Brain Sciences (MDPI), Combinatorial Chemistry & High Throughput Screening (Bentham Science), Molecules (MDPI), Current Topics in Medicinal Chemistry (Bentham Science), Current Drug Targets (Bentham Science)

Teaching Experience:

  • Professor at Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, Kochi, India, since April 2022
  • Associate Professor and Assistant Professor at various institutions in India prior to current position

Invited Talks:

  • Presented internationally and nationally on topics related to drug design, molecular docking, and medicinal chemistry.

Awards and Recognition:

  • Recognized with multiple awards including Top 2% Scientists from Stanford, Amrita Publication Research Award, Best International Collaborator Award, Chancellor’s Publication Award, Publication Merit Award, and Best Resource Person Award at National College of Pharmacy.

Patents:

  • Granted patents on compositions for neurological disorders and therapeutic agents.

Publications

  1. Elucidating molecular mechanism and chemical space of chalcones through biological networks and machine learning approaches
    • Authors: Manaithiya, A., Bhowmik, R., Acharjee, S., Parkkila, S., Aspatwar, A., Mathew, B.
    • Year: 2024
    • Citations: 0
  2. Machine learning driven web-based app platform for the discovery of monoamine oxidase B inhibitors
    • Authors: Kumar, S., Bhowmik, R., Oh, J.M., Kim, H., Mathew, B.
    • Year: 2024
    • Citations: 3
  3. Development of morpholine ring-bearing halogenated α,β-unsaturated ketones as selective monoamine oxidase-B inhibitors
    • Authors: Lee, J., Parmbil, S.K., Pandit, N.K., Kim, H., Mathew, B.
    • Year: 2024
    • Citations: 0
  4. Isatin-tethered halogen-containing acylhydrazone derivatives as monoamine oxidase inhibitor with neuroprotective effect
    • Authors: Kumar, S., Oh, J.M., Prabhakaran, P., Kim, H., Mathew, B.
    • Year: 2024
    • Citations: 3
  5. MzDOCK: A free ready-to-use GUI-based pipeline for molecular docking simulations
    • Authors: Kabier, M., Gambacorta, N., Trisciuzzi, D., Nicolotti, O., Mathew, B.
    • Year: 2024
    • Citations: 0
  6. Design and Synthesis of the Linezolid Bioisosteres to Resolve the Serotonergic Toxicity Associated with Linezolid
    • Authors: Girase, R.T., Ahmad, I., Oh, J.M., Kim, H., Patel, H.M., Mathew, B.
    • Year: 2024
    • Citations: 0
  7. MAO-B Inhibitor (2E)-3-(4-Bromophenyl)-1-(1H-indol-3-yl) prop-2-en-1-one as a Neuroprotective Agent Against Alzheimer’s Disease
    • Authors: Sasidharan, R., Mohanan, R., Kukreti, N., Manju, S.L., Mathew, B.
    • Year: 2024
    • Citations: 0
  8. Correction to: Targeting cellular batteries for the therapy of neurological diseases (Environmental Science and Pollution Research)
    • Authors: Arora, A., Behl, T., Sehgal, A., Mathew, B., Bungau, S.
    • Year: 2024
    • Citations: 0
  9. Chalcones with N-Methylpiperazine Moiety: Synthesis, Monoamine Oxidase Inhibition, Neuroprotective Effect and Computer Simulation Study
    • Authors: Jayan, J., Trisciuzzi, D., Benny, F., Nicolotti, O., Mathew, B.
    • Year: 2024
    • Citations: 0
  10. A structure-based approach to explore novel COX-2 inhibitors using pharmacophore modelling, 3D-QSAR analysis, virtual screening and dynamics simulation study
    • Authors: Krishnendu, P.R., Benny, S., Kumar, S., Zachariah, S.M., Mathew, B.
    • Year: 2024
    • Citations: 3

 

 

Bijo Mathew | Medicinal Chemistry | Best Researcher Award

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