Yujie Guo | Genomics | Best Researcher Award

Dr. Yujie Guo | Genomics | Best Researcher Award 

Dr. Yujie Guo, Henan Agricultural University, China

Dr. Yujie Guo is a Supervisor at Henan Agricultural University, China, specializing in poultry genetics. Her research focuses on uncovering molecular mechanisms and advantageous genes in indigenous chicken breeds, especially under stress conditions. Her doctoral work on Gushi chickens’ immune response under stress led to over 10 publications in high-impact journals such as Genes, Molecular Immunology, and Journal of Proteomics, and earned her a national invention patent. With 4 research projects completed, 53 citations, and significant contributions to epigenetic regulation and heat tolerance breeding strategies, she is a strong candidate for the Best Researcher Award.

Profile

Scopus

🎓 Early Academic Pursuits

Dr. Yujie Guo began her academic journey with a deep-seated interest in animal science, particularly the genetic and physiological aspects of poultry. Her early education was marked by a persistent curiosity about how genetics influence performance traits in animals. This passion led her to pursue doctoral studies focused on poultry science, where she honed her expertise in molecular genetics and immunology. During her Ph.D., she meticulously investigated the regulatory mechanisms behind stress-induced immune responses in Gushi chickens—an indigenous breed known for its resilience and adaptability. Her academic training laid a solid foundation for a career centered on translational research with real-world implications for poultry health and breeding.

👩‍🔬 Professional Endeavors

As a Supervisor at Henan Agricultural University, Dr. Guo plays a multifaceted role encompassing research, mentorship, and academic leadership. In her professional capacity, she oversees advanced research projects that bridge molecular biology and animal husbandry. Her supervision goes beyond administrative tasks—she actively participates in the experimental design, data interpretation, and scientific writing processes of numerous research initiatives.

Dr. Guo has successfully led and contributed to four major research projects, each delving into the genetic architecture and epigenetic regulation of key traits in indigenous chickens. Her work has directly contributed to a deeper understanding of how stress, particularly heat stress, affects poultry at a molecular level, enabling the development of targeted strategies for improving heat tolerance in commercial breeds.

🧬 Contributions and Research Focus

Dr. Guo’s research is at the cutting edge of avian molecular genetics. Her central focus lies in identifying and utilizing advantageous genes in indigenous chicken breeds—a field that holds tremendous promise for enhancing global food security. By targeting breeds that are naturally resistant to harsh environments, she is helping to lay the groundwork for more sustainable poultry farming practices.

Her doctoral research broke new ground in understanding immune modulation under stress, specifically in Gushi chickens. This work has been instrumental in elucidating how certain genes are regulated under thermal stress, leading to enhanced immunity and survival. These findings not only support the theoretical framework of epigenetic regulation in poultry but also provide practical solutions for breeding programs aimed at increasing heat tolerance.

To date, Dr. Guo has authored more than 10 peer-reviewed articles published in internationally recognized journals like Genes, Molecular Immunology, Journal of Proteomics, and Research in Veterinary Science. Her scholarly output reflects a consistent focus on innovative genetic methodologies and practical breeding solutions.

🏅 Accolades and Recognition

Dr. Guo’s contributions to poultry science have not gone unnoticed. Her research has earned her a national invention patent, a testament to the originality and applicability of her work. With a citation index of 53, her research has begun to influence ongoing studies in molecular poultry science across China and beyond.

Although still early in her career, her work has received commendation for its relevance and scientific rigor. She has become a respected figure in her field, known for her detailed approach, clarity of thought, and unwavering commitment to scientific excellence.

🌍 Impact and Influence

Dr. Guo’s work holds immense importance in the face of global challenges such as climate change and food insecurity. Her research into heat stress resistance has implications not just for China but for poultry industries worldwide, particularly in tropical and subtropical regions.

Her findings have offered actionable insights into the genetic markers associated with stress tolerance, making it easier for breeders and agricultural scientists to develop robust poultry lines. Moreover, her research contributes to the global discourse on sustainable agriculture and animal welfare, positioning her as an emerging thought leader in the field.

🕊️ Legacy and Future Contributions

Looking forward, Dr. Yujie Guo aims to expand her research scope by engaging in international collaborations and integrating cutting-edge technologies like CRISPR gene editing and multi-omics approaches. She envisions a future where poultry breeding is fully optimized for both productivity and adaptability, ensuring food sustainability even under extreme environmental conditions.

Her long-term goal is to establish a center of excellence in avian genetics at Henan Agricultural University, where young scientists can be mentored and new breeding technologies can be developed. Through her work, Dr. Guo hopes to leave a legacy of innovation, sustainability, and academic integrity.

📖 Publication Top Notes

Author: Z., Luo, Zhixuan, Y., Gong, Yujie, Q., Li, Qiang, X., Kang, Xiangtao, R., Jiang, Ruirui

Journal: Poultry science

Year: 2025

Author: J., Zhang, Jun, Y., Gong, Yujie, Y., Zhu, Yidan, Z., Li, Zhuanjian, R., Jiang, Ruirui

Journal: Poultry science

Year: 2025

Author: J., Li, Jianzeng, X., Liu, Xinxin, C., Cai, Chunxia, X., Kang, Xiangtao, R., Han, Ruili

Journal: Poultry science

Year: 2024

 

Zu-Chian Chiang | Biochemistry | Best Researcher Award | 13347

Dr. Zu-Chian Chiang | Biochemistry | Best Researcher Award 

Dr. Zu-Chian Chiang, Fujian Normal University, China

Dr. Zu-Chian Chiang is a postdoctoral fellow at the Biomedical Research Center of Southern China, Fujian Normal University, China, with a rich background in materials and chemical engineering. His research contributions span antibody-drug conjugates (ADCs), functional peptide synthesis, biomaterials for regenerative medicine, and aptamer-based cancer therapy. His work has geographic impact across Taiwan and Mainland China, contributing to translational medicine and oncology through collaborative efforts with prestigious institutions like Academia Sinica and National Taiwan University. His applied research in ADCs and biomaterial scaffolds directly supports cancer treatment innovations. Notable projects include the development of CD47-targeting ADCs for non-small cell lung cancer, and thalidomide-PD1 combinations for enhanced immunotherapy. His publications in Frontiers in Oncology, PLOS ONE, and Current Pharmaceutical Biotechnology highlight his influence in drug delivery and cancer therapeutics. In the vector control domain, his scaffold research contributes to potential localized drug delivery systems. Dr. Chiang has received awards such as the Science and Technology Commissioner honor from Quanzhou and the Biotech Elite Training Award. His achievements exemplify impactful biomedical research with real-world therapeutic implications.

Profile

Scopus

🌱 Early Academic Pursuits

Dr. Zu-Chian Chiang embarked on his scientific journey with a passion for chemistry and materials science. He earned his Master’s Degree in Chemistry from Tunghai University, Taiwan (2005–2007), under the guidance of Prof. Feng-Di Lung. Building on this solid foundation, he pursued his Ph.D. in Materials and Chemical Engineering at National United University, Taiwan (2008–2014). During his doctoral studies, he was mentored by Prof. An-Chong Chao and co-advised by Dr. Guo-Chung Dong, focusing on biomaterials and nanomedicine.

Even as a student, Dr. Chiang demonstrated exceptional academic capabilities, earning scholarships and recognition for his innovative research. His academic training laid the groundwork for his future contributions in biomedical engineering and cancer therapeutics.

🧪 Professional Endeavors

Dr. Chiang has held several prestigious postdoctoral positions. His professional journey reflects a commitment to interdisciplinary collaboration and translational research:

  • Postdoctoral Fellow at the Biomedical Research Center of Southern China, Fujian Normal University (2019–Present), working under Prof. Qi Chen.

  • Postdoctoral Fellow at the Institute of Biological Chemistry, Academia Sinica, Taiwan (2016–2019), contributing to the Taiwan Protein Project (TPP) and the Technical Support Platform Spindle Project (TSPA).

  • Postdoctoral Fellow at the Clinical Trial Center, National Taiwan University Hospital (2015–2016), supported by Taiwan’s prestigious Biotech Elite Training Program.

Throughout these roles, Dr. Chiang has engaged in cutting-edge biomedical research with direct implications for drug development and clinical applications.

🔬 Contributions and Research Focus

Dr. Chiang’s research centers on innovative therapeutic materials and drug delivery systems, particularly in cancer therapy. His core interests include:

  • Antibody-Drug Conjugates (ADCs): Targeted cancer therapies such as HER2-positive and CD47-specific ADCs.

  • Functional Peptide Synthesis for bone tissue engineering and cancer inhibition.

  • Bio-Micro-Macro Molecular Materials for regenerative medicine.

  • Aptamer Development as modulators in therapeutic settings.

Notable publications include research on CD47-targeting ADCs (Frontiers in Oncology, 2022) and HER2-positive ADCs (PLOS ONE, 2020). His work on dexamethasone-immobilized chitosan scaffolds and chitosan-caffeic acid hybrids also provides valuable insights into localized drug delivery and tissue engineering.

🏆 Accolades and Recognition

Dr. Chiang’s dedication has been acknowledged through numerous awards:

  • 🥇 Science and Technology Commissioner, Quanzhou, Fujian Province (2020)

  • 🥇 Biotech Elite Training Award, National Taiwan University & Ministry of Science and Technology (2016)

  • 🥇 Chung Hwa Rotary Doctoral Program Award, Taiwan (2012)

  • 🥇 Outstanding Doctoral Scholarship, National United University (2010)

  • 🥇 Master’s Program Scholarship, Hunan Fellow Association of Taiwan (2007)

  • 🥇 Rotary Leadership Award, Miaoli Southeastern Xindong Satellite Rotary Club (2017)

These accolades affirm his position as a respected figure in the fields of biomedical chemistry and translational medicine.

🌍 Impact and Influence

Dr. Chiang’s work has made a geographic impact spanning Taiwan and Mainland China. His collaborative research in academia and clinical centers bridges the gap between laboratory research and therapeutic application. He actively contributes as a peer reviewer for the International Journal of Biological Macromolecules, influencing scientific standards and publication quality globally.

He is also engaged in community service through leadership in Rotary International, fostering science-driven community development and education.

🌟 Legacy and Future Contributions

Dr. Chiang’s legacy is being built on the foundation of scientific excellence, mentorship, and translational impact. His research not only pushes the boundaries of biomedical engineering but also aims to enhance the effectiveness of cancer treatments in clinical practice. With a commitment to developing next-generation targeted therapies and biomaterial scaffolds, Dr. Chiang is poised to shape the future of personalized medicine and regenerative technologies.

Looking ahead, he aims to establish interdisciplinary collaborations and contribute to global health initiatives, making life-saving therapies more effective and accessible.

Publication Top Notes

Development of Novel CD47-Specifific ADCs Possessing High Potency Against Non-Small Cell Lung Cancer in vitro and in vivo. 

Author: Z.C., Chiang, Zu Chian, S., Fang, Shubin, Y., Shen, Yangkun, J., Lin, Jizhen, Q., Chen, Qi

Journal: Frontiers in Oncology,

Year: 2022

Preparation and characterization of dexamethasone-immobilized chitosan scaffold

Author: Z.C., Chiang, Zu Chian, S., Yu, Shuhuei, A., Chao, Anchong, G.C., Dong, Guo Chung

Journal: Journal of Bioscience and Bioengineering, 

Year: 2012