Pratiksha Kshirsagar | Pre-clinical pharmacology | Best Researcher Award | 13450

Ms. Pratiksha Kshirsagar | Pre-clinical pharmacology | Best Researcher Award

Ms. Pratiksha Kshirsagar, University of Nebraska Medical Center, United States

Ms. Pratiksha Kshirsagar is a dedicated pharmaceutical scientist currently pursuing her Ph.D. in Pharmaceutical Sciences at the University of Nebraska Medical Center (UNMC), USA. With strong academic credentials and hands-on research experience in both India and the U.S., she specializes in bioanalytical method development, preclinical pharmacokinetics, and drug delivery systems. Her work includes the development and validation of LC-MS/MS methods and conducting in vitro and in vivo DMPK studies for novel therapeutics targeting medulloblastoma. She has co-authored several peer-reviewed publications and presented her findings at national and international conferences. Ms. Kshirsagar is also a recipient of the UNMC Dean of Graduate Studies Conference Attendance Award and remains committed to advancing pharmaceutical research and translational drug development.

Profile

ORCID

🎓 Early Academic Pursuits

Pratiksha Kshirsagar’s academic journey is marked by consistent dedication and a keen interest in pharmaceutical sciences. Her educational foundation was laid at Savitribai Phule Pune University, where she earned both her Bachelor of Pharmacy (2016–2020) with an SGPA of 7.7/10 and a Master of Pharmacy in Pharmaceutics (2020–2022), graduating with distinction (SGPA: 8.96/10). These formative years laid the groundwork for her strong research acumen and laboratory skills. Keen to explore further, she transitioned to the University of Nebraska Medical Center (UNMC), USA, where she pursued a Master of Pharmaceutical Sciences (2022–2024). Her academic growth culminated in her enrollment in the Ph.D. program in Pharmaceutical Sciences (2024–2029). With a GPA of 3.6/4.0, her progress has been both steady and impressive. Simultaneously, she earned a Certificate in Applied Biostatistics with a perfect GPA of 4.0/4.0, showcasing her commitment to interdisciplinary learning and data-driven research.

đź§Ş Professional Endeavors

Pratiksha’s professional experience is deeply intertwined with her academic path, reflecting a rare blend of scholarly rigor and hands-on application. At UNMC, under the mentorship of Dr. Daryl J. Murry, she has worked extensively as a graduate research assistant and student researcher, contributing to the development and validation of LC-MS/MS bioanalytical methods for novel small molecules and RIPTACs. Her earlier professional journey in India involved impactful research under Dr. Smita S. Pimple, where she explored micro-emulsions using essential oils and carrier oils for skincare applications. This early exposure to formulation science, coupled with analytical chemistry, gave her a solid foundation in pharmaceutics and laboratory research.

🔬 Contributions and Research Focus

Pratiksha’s primary research focus lies in drug metabolism and pharmacokinetics (DMPK), with an emphasis on preclinical evaluation of novel therapeutic agents. Her notable contributions include the in-depth pharmacokinetic analysis of EPZ015666 and JNJ-64619178 for medulloblastoma treatment, reflecting her role in advancing pediatric cancer therapy.

Her technical expertise spans several key areas:

  • LC-MS/MS bioanalytical method development

  • In-vitro studies like metabolic stability, protein binding, and drug transporter assays

  • In-vivo animal studies, including oral/IV dosing and tissue distribution

  • Use of Phoenix WinNonlin, GraphPad Prism, and other analytical tools for pharmacokinetic modeling

Moreover, she contributed to the design, characterization, and stability testing of advanced nano drug delivery systems such as S-SNEDDS (Solid Self-Nanoemulsifying Drug Delivery System), which demonstrates her interdisciplinary knowledge.

🏅 Accolades and Recognition

Pratiksha’s dedication has earned her notable recognition throughout her academic and research journey. She was awarded the UNMC Dean of Graduate Studies Conference Attendance Award in 2023, underscoring her academic excellence and potential for contribution at scientific forums.

She actively participated in esteemed conferences such as:

  • American Association of Pharmaceutical Scientists (AAPS), Oct 2023

  • UNMC College of Pharmacy Research Day, May 2023

  • CHRI Pediatric Research Forum, May 2023

In earlier academic years, she was involved in state and national level conferences and poster competitions, including the Medical Coding & E-Poster Competition (2020) and a State Level Seminar on Natural Products Research (2018).

🌍 Impact and Influence

Pratiksha’s research holds real-world significance. Her work on small molecule therapeutics for medulloblastoma contributes to the body of knowledge addressing rare pediatric brain cancers, potentially guiding future clinical interventions. Her cross-functional approach—merging analytical chemistry, pharmacology, and pharmaceutical formulation—makes her an invaluable contributor to translational medicine. She has also co-authored several scholarly publications and book chapters on nanotechnology, drug delivery, and antiviral drug challenges, reinforcing her growing influence in the academic community. These contributions are cited in peer-reviewed journals and academic textbooks, evidencing her thought leadership.

đź”® Legacy and Future Contributions

As Pratiksha continues her Ph.D. journey, her trajectory suggests a future as a leading scientist in pharmaceutical research and drug development. Her interests align with solving complex challenges in drug delivery, pharmacokinetics, and personalized medicine. Looking ahead, she aims to bridge the gap between bench-side research and bedside applications, translating scientific breakthroughs into therapeutic realities. Whether in academia, industry, or clinical collaborations, her vision is clear: to contribute meaningfully to global health innovation.

đź“„ Publication Top Notes

Crossing the Blood–Brain Barrier: Innovations in Receptor- and Transporter-Mediated Transcytosis Strategies

Contributors: Ling Ding; Pratiksha Kshirsagar; Prachi Agrawal; Daryl J. Murry

Journal: Pharmaceutics

Year: 2025

Preparation and Characterization of Advanced Nano medicine For Malaria: Box Behnken Design Approach

Contributors: Anuradha G. More; Parag R. Potbhare; Padmaja S. Kore; Praveen D. Chaudhari; Pratiksha U. Kshirsagar; Radhika R. Baheti; Surbhi C. Gupta

Journal: International Journal of Life Science and Pharma Research

Year: 2022

Touhidul Islam Tanim | Pharmacy | Young Scientist Award | 13317

Mr. Touhidul Islam Tanim | Pharmacy | Young Scientist Award

Mr. Touhidul Islam Tanim, Gopalgonj Science and Technology University, Bangladesh

Mr. Touhidul Islam Tanim is a dedicated researcher from Gopalganj Science and Technology University, Bangladesh, with expertise in pharmaceutical sciences. His research focuses on drug discovery, molecular docking, and pharmacological studies. He has co-authored multiple peer-reviewed publications in reputable journals, including Journal of Functional Foods and Khulna University Studies. As a Research Assistant at BioLuster Research Center Ltd., he conducts in-vivo experiments and contributes to scholarly writing. His work has earned him several accolades, including recognition in bioinformatics and computational biology. With a strong academic background and industry training, he is committed to advancing medical science for human health improvement.

Profile

Google Scholar

Early Academic Pursuits 🎓

Mr. Touhidul Islam Tanim began his academic journey with a strong foundation in science, showcasing excellence from an early stage. He completed his Secondary School Certificate (SSC) in 2015 from Barishal Zilla School with an outstanding GPA of 5.00 out of 5.00. His academic brilliance continued through his Higher Secondary Certificate (HSC) in 2017 at Govt. Syed Hatem Ali College, achieving the same remarkable GPA.

With a passion for pharmaceutical sciences and medical research, he pursued a Bachelor of Pharmacy (B. Pharm) at Gopalganj Science and Technology University (2018-2022), securing a CGPA of 3.49 out of 4.00. Currently, he is pursuing his Master of Pharmacy (M. Pharm, Thesis) at the same institution (2023-2025), with an impressive CGPA of 3.76 out of 4.00. His academic excellence is further highlighted by his IELTS score of 7, indicating strong proficiency in English, which aids in his global research collaborations.

Professional Endeavors 🔬

With a deep passion for drug discovery, molecular docking, and pharmacological studies, Mr. Tanim embarked on his professional journey as a Research Assistant (RA) at BioLuster Research Center Ltd. in 2024. His responsibilities include:

  • Conducting in-vivo and in-silico pharmacological experiments
  • Performing extensive literature reviews
  • Writing research and review articles for international publications
  • Exploring bioinformatics applications in drug research

Additionally, he underwent industrial training at General Pharmaceuticals Ltd., where he gained hands-on experience in quality control, assurance, microbiology, product development, and regulatory compliance.

Contributions and Research Focus đź§Ş

Mr. Tanim’s research is dedicated to human disease treatment, with a focus on natural compounds, pharmacodynamics, and drug interactions. His key research contributions include:

Published Research Works đź“–

  1. Antiemetic activity of Sesamol – Explores the serotonergic and dopaminergic pathways in Journal of Functional Foods
  2. Clot lysis and membrane protection potentials of Cheilanthes tenuifolia methanolic leaf extract – Published in Khulna University Studies
  3. 6-Shogaol: A Short Review – Published in Clinical Research Notes
  4. Sesamol’s anti-inflammatory and synergistic properties with Celecoxib and Ketoprofen (DOI: https://doi.org/10.1016/j.ctmp.2025.200203)

Manuscripts Under Review đź“‘

  • Sesamol’s Antidiarrheal Potential in Castor Oil-Induced Diarrheal Models
  • Anxiolytic Effects of Citral in Swiss Albino Mice through the GABAergic interaction pathway
  • Quercetin’s Role in Modulating d-pinitol-mediated Anxiolytic-like Effects

His extensive research work combines in-vivo, in-silico, and molecular docking methodologies, contributing significantly to pharmacology, computational biology, and drug discovery.

Accolades and Recognition 🏆

Mr. Tanim’s dedication to research has earned him several prestigious awards and achievements, including:

  • Finalist Certificate from the 1st Biology and Bioinformatics Olympiad organized by BioPC
  • Certificate from Online Workshop on Article Writing & Computational Studies by BioLuster Research Center Ltd.
  • Membership Certificate from GSTU Research and Higher Studies Society

His publications, ongoing research, and professional contributions are widely recognized in the pharmaceutical and medical research communities.

Impact and Influence 🌍

As an emerging researcher, Mr. Tanim’s work is reshaping pharmaceutical sciences, particularly in:

  • Vector Control – His studies on sesamol’s anti-inflammatory and antiemetic properties have potential applications in treating gastrointestinal disorders.
  • Collaborative Efforts – His partnerships with international researchers, industry experts, and academic institutions enhance knowledge exchange.
  • Applied Research – His focus on natural bioactive compounds contributes to drug development and disease management.
  • Geographic Impact – His research spans Bangladesh, the Middle East, and Western academia, making his work globally relevant.

His efforts in bioinformatics, molecular docking, and pharmacology position him as a promising innovator in medical science.

Legacy and Future Contributions 🚀

Looking ahead, Mr. Tanim aims to:

  • Develop novel drug formulations based on plant-based bioactive compounds
  • Enhance collaborations with global research institutions and pharmaceutical industries
  • Bridge the gap between computational biology and pharmacology for effective drug screening
  • Inspire young researchers through mentorship, training, and scholarly contributions

His dedication, expertise, and research impact position him as a future leader in pharmaceutical innovation.

 

Bijo Mathew | Medicinal Chemistry | Best Researcher Award

Prof Dr. Bijo Mathew | Medicinal Chemistry | Best Researcher Award

Professor at Amrita School of Pharmacy India.

Prof. Dr. Bijo Mathew is a distinguished academic in pharmaceutical sciences, currently serving as a Professor at Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, Kochi. With a robust background in molecular docking and drug design using AutoDock 4.2, Biovia, and Glide, he contributes significantly as Section Editor for Coronaviruses (BenthamScience) and Editorial Member for several prestigious journals. Dr. Mathew’s teaching career spans from Assistant Professor to his current role, imparting knowledge across various institutions in India. He is a sought-after speaker, delivering talks internationally and nationally on drug design and medicinal chemistry. Recognized as one of the Top 2% Scientists by Stanford, he has received multiple awards including the Amrita Publication Research Award and Best International Collaborator Award. Dr. Mathew holds patents for compositions addressing neurological disorders, underscoring his commitment to advancing pharmaceutical research and education.

Professional Profiles:

🎓 Education

Prof. Dr. Bijo Mathew boasts a distinguished academic journey in pharmaceutical sciences, culminating in a Ph.D. from Jawaharlal Nehru Technological University, Hyderabad, India, specializing in Pharmaceutical Science. Prior to his doctoral studies, he completed his Master’s in Pharmaceutical Chemistry and Bachelor’s in Pharmacy at The Tamilnadu Dr. M.G.R. Medical University, Chennai, and his pre-degree at Mahatma Gandhi University, Kottayam, India. His doctoral research under the guidance of Dr. A. Jerad Suresh focused on the synthesis, characterization, and pharmacological evaluation of heterocyclic derivatives, contributing significantly to the field. Prof. Mathew’s academic journey is marked by a commitment to advancing pharmaceutical knowledge, evident in his extensive expertise across various domains of pharmaceutical research, including molecular docking, dynamics, and pharmacophore mapping. His educational foundation and research acumen continue to drive innovative contributions in drug discovery and development, positioning him as a prominent figure in academia and pharmaceutical research.

Area of Interest and Expertise

Prof. Dr. Bijo Mathew’s research interests encompass a diverse array of fields within pharmaceutical chemistry and drug discovery. His expertise spans the chemistry and biological exploration of various classes of compounds such as chalcones and isatins. He is involved in the synthesis and pharmacological evaluation of heterocyclic nuclei including benzimidazole, thiadiazole, pyrimidine, furan, pyrazoline, and thiazole derivatives, focusing on their potential as CNS depressants, anticonvulsants, anticancer agents, antioxidants, and neuroprotective compounds. Dr. Mathew specializes in designing inhibitors for key enzymes like MAO, AChE, BACE1, and Hsp90, utilizing techniques such as monowave-assisted synthesis and structural elucidation through IR, NMR, and MASS spectroscopy. His research also extends to molecular docking, dynamics, pharmacophore mapping, and 3D-QSAR studies, as well as the isolation and computational analysis of natural secondary metabolites from medicinal plants.

Expertise in Software:

  • AutoDock 4.2, Biovia, Glide

Editorial Contributions:

  • Section Editor for Coronaviruses (BenthamScience)
  • Editorial Member for Brain Sciences (MDPI), Combinatorial Chemistry & High Throughput Screening (Bentham Science), Molecules (MDPI), Current Topics in Medicinal Chemistry (Bentham Science), Current Drug Targets (Bentham Science)

Teaching Experience:

  • Professor at Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, Kochi, India, since April 2022
  • Associate Professor and Assistant Professor at various institutions in India prior to current position

Invited Talks:

  • Presented internationally and nationally on topics related to drug design, molecular docking, and medicinal chemistry.

Awards and Recognition:

  • Recognized with multiple awards including Top 2% Scientists from Stanford, Amrita Publication Research Award, Best International Collaborator Award, Chancellor’s Publication Award, Publication Merit Award, and Best Resource Person Award at National College of Pharmacy.

Patents:

  • Granted patents on compositions for neurological disorders and therapeutic agents.

Publications

  1. Elucidating molecular mechanism and chemical space of chalcones through biological networks and machine learning approaches
    • Authors: Manaithiya, A., Bhowmik, R., Acharjee, S., Parkkila, S., Aspatwar, A., Mathew, B.
    • Year: 2024
    • Citations: 0
  2. Machine learning driven web-based app platform for the discovery of monoamine oxidase B inhibitors
    • Authors: Kumar, S., Bhowmik, R., Oh, J.M., Kim, H., Mathew, B.
    • Year: 2024
    • Citations: 3
  3. Development of morpholine ring-bearing halogenated α,β-unsaturated ketones as selective monoamine oxidase-B inhibitors
    • Authors: Lee, J., Parmbil, S.K., Pandit, N.K., Kim, H., Mathew, B.
    • Year: 2024
    • Citations: 0
  4. Isatin-tethered halogen-containing acylhydrazone derivatives as monoamine oxidase inhibitor with neuroprotective effect
    • Authors: Kumar, S., Oh, J.M., Prabhakaran, P., Kim, H., Mathew, B.
    • Year: 2024
    • Citations: 3
  5. MzDOCK: A free ready-to-use GUI-based pipeline for molecular docking simulations
    • Authors: Kabier, M., Gambacorta, N., Trisciuzzi, D., Nicolotti, O., Mathew, B.
    • Year: 2024
    • Citations: 0
  6. Design and Synthesis of the Linezolid Bioisosteres to Resolve the Serotonergic Toxicity Associated with Linezolid
    • Authors: Girase, R.T., Ahmad, I., Oh, J.M., Kim, H., Patel, H.M., Mathew, B.
    • Year: 2024
    • Citations: 0
  7. MAO-B Inhibitor (2E)-3-(4-Bromophenyl)-1-(1H-indol-3-yl) prop-2-en-1-one as a Neuroprotective Agent Against Alzheimer’s Disease
    • Authors: Sasidharan, R., Mohanan, R., Kukreti, N., Manju, S.L., Mathew, B.
    • Year: 2024
    • Citations: 0
  8. Correction to: Targeting cellular batteries for the therapy of neurological diseases (Environmental Science and Pollution Research)
    • Authors: Arora, A., Behl, T., Sehgal, A., Mathew, B., Bungau, S.
    • Year: 2024
    • Citations: 0
  9. Chalcones with N-Methylpiperazine Moiety: Synthesis, Monoamine Oxidase Inhibition, Neuroprotective Effect and Computer Simulation Study
    • Authors: Jayan, J., Trisciuzzi, D., Benny, F., Nicolotti, O., Mathew, B.
    • Year: 2024
    • Citations: 0
  10. A structure-based approach to explore novel COX-2 inhibitors using pharmacophore modelling, 3D-QSAR analysis, virtual screening and dynamics simulation study
    • Authors: Krishnendu, P.R., Benny, S., Kumar, S., Zachariah, S.M., Mathew, B.
    • Year: 2024
    • Citations: 3