Yujie Guo | Genomics | Best Researcher Award

Dr. Yujie Guo | Genomics | Best Researcher Award 

Dr. Yujie Guo, Henan Agricultural University, China

Dr. Yujie Guo is a Supervisor at Henan Agricultural University, China, specializing in poultry genetics. Her research focuses on uncovering molecular mechanisms and advantageous genes in indigenous chicken breeds, especially under stress conditions. Her doctoral work on Gushi chickens’ immune response under stress led to over 10 publications in high-impact journals such as Genes, Molecular Immunology, and Journal of Proteomics, and earned her a national invention patent. With 4 research projects completed, 53 citations, and significant contributions to epigenetic regulation and heat tolerance breeding strategies, she is a strong candidate for the Best Researcher Award.

Profile

Scopus

🎓 Early Academic Pursuits

Dr. Yujie Guo began her academic journey with a deep-seated interest in animal science, particularly the genetic and physiological aspects of poultry. Her early education was marked by a persistent curiosity about how genetics influence performance traits in animals. This passion led her to pursue doctoral studies focused on poultry science, where she honed her expertise in molecular genetics and immunology. During her Ph.D., she meticulously investigated the regulatory mechanisms behind stress-induced immune responses in Gushi chickens—an indigenous breed known for its resilience and adaptability. Her academic training laid a solid foundation for a career centered on translational research with real-world implications for poultry health and breeding.

👩‍🔬 Professional Endeavors

As a Supervisor at Henan Agricultural University, Dr. Guo plays a multifaceted role encompassing research, mentorship, and academic leadership. In her professional capacity, she oversees advanced research projects that bridge molecular biology and animal husbandry. Her supervision goes beyond administrative tasks—she actively participates in the experimental design, data interpretation, and scientific writing processes of numerous research initiatives.

Dr. Guo has successfully led and contributed to four major research projects, each delving into the genetic architecture and epigenetic regulation of key traits in indigenous chickens. Her work has directly contributed to a deeper understanding of how stress, particularly heat stress, affects poultry at a molecular level, enabling the development of targeted strategies for improving heat tolerance in commercial breeds.

🧬 Contributions and Research Focus

Dr. Guo’s research is at the cutting edge of avian molecular genetics. Her central focus lies in identifying and utilizing advantageous genes in indigenous chicken breeds—a field that holds tremendous promise for enhancing global food security. By targeting breeds that are naturally resistant to harsh environments, she is helping to lay the groundwork for more sustainable poultry farming practices.

Her doctoral research broke new ground in understanding immune modulation under stress, specifically in Gushi chickens. This work has been instrumental in elucidating how certain genes are regulated under thermal stress, leading to enhanced immunity and survival. These findings not only support the theoretical framework of epigenetic regulation in poultry but also provide practical solutions for breeding programs aimed at increasing heat tolerance.

To date, Dr. Guo has authored more than 10 peer-reviewed articles published in internationally recognized journals like Genes, Molecular Immunology, Journal of Proteomics, and Research in Veterinary Science. Her scholarly output reflects a consistent focus on innovative genetic methodologies and practical breeding solutions.

🏅 Accolades and Recognition

Dr. Guo’s contributions to poultry science have not gone unnoticed. Her research has earned her a national invention patent, a testament to the originality and applicability of her work. With a citation index of 53, her research has begun to influence ongoing studies in molecular poultry science across China and beyond.

Although still early in her career, her work has received commendation for its relevance and scientific rigor. She has become a respected figure in her field, known for her detailed approach, clarity of thought, and unwavering commitment to scientific excellence.

🌍 Impact and Influence

Dr. Guo’s work holds immense importance in the face of global challenges such as climate change and food insecurity. Her research into heat stress resistance has implications not just for China but for poultry industries worldwide, particularly in tropical and subtropical regions.

Her findings have offered actionable insights into the genetic markers associated with stress tolerance, making it easier for breeders and agricultural scientists to develop robust poultry lines. Moreover, her research contributes to the global discourse on sustainable agriculture and animal welfare, positioning her as an emerging thought leader in the field.

🕊️ Legacy and Future Contributions

Looking forward, Dr. Yujie Guo aims to expand her research scope by engaging in international collaborations and integrating cutting-edge technologies like CRISPR gene editing and multi-omics approaches. She envisions a future where poultry breeding is fully optimized for both productivity and adaptability, ensuring food sustainability even under extreme environmental conditions.

Her long-term goal is to establish a center of excellence in avian genetics at Henan Agricultural University, where young scientists can be mentored and new breeding technologies can be developed. Through her work, Dr. Guo hopes to leave a legacy of innovation, sustainability, and academic integrity.

📖 Publication Top Notes

Author: Z., Luo, Zhixuan, Y., Gong, Yujie, Q., Li, Qiang, X., Kang, Xiangtao, R., Jiang, Ruirui

Journal: Poultry science

Year: 2025

Author: J., Zhang, Jun, Y., Gong, Yujie, Y., Zhu, Yidan, Z., Li, Zhuanjian, R., Jiang, Ruirui

Journal: Poultry science

Year: 2025

Author: J., Li, Jianzeng, X., Liu, Xinxin, C., Cai, Chunxia, X., Kang, Xiangtao, R., Han, Ruili

Journal: Poultry science

Year: 2024

 

XianLing Cao | Genetics and Genomics | Best Researcher Award

Mr. XianLing Cao | Genetics and Genomics | Best Researcher Award

Doctor of Medicine, MD at Shandong University of Traditional Chinese Medicine, China; Fudan University, China.

Dr. Xianling Cao is a dedicated researcher specializing in Obstetrics and Gynecology with a focus on Reproductive Medicine and Traditional Chinese Medicine (TCM). Holding a Doctor of Medicine degree, she completed her education at esteemed institutions such as Shandong University of Traditional Chinese Medicine and Fudan University in China. Dr. Cao’s professional journey includes postdoctoral research at Shandong University’s Affiliated Hospital and previous academic contributions at Fudan University’s Obstetrics and Gynecology Hospital. With a keen interest in placental dysfunction disorders and TCM interventions, she has published extensively, including SCI papers and collaborative projects. Dr. Cao’s work demonstrates a commitment to advancing knowledge in her field and improving reproductive health outcomes.

Professional Profiles:

Education:

Dr. Xianling Cao holds a Doctor of Medicine degree in Obstetrics and Gynecology, specializing in Reproductive Medicine and Traditional Chinese Medicine. She obtained her MD from Shandong University of Traditional Chinese Medicine, China, and furthered her education at Fudan University, China. With a focus on advancing women’s health, Dr. Cao’s academic journey has been marked by rigorous training and research endeavors. Her expertise encompasses the intricate interplay between modern medical practices and traditional healing modalities. Throughout her educational pursuit, Dr. Cao has demonstrated a steadfast commitment to expanding knowledge in her field, positioning herself as a promising scholar at the intersection of Western medicine and traditional Chinese therapies.

Professional Experience

Dr. Xianling Cao brings a wealth of professional experience in the field of Obstetrics and Gynecology, with a specialized focus on Reproductive Medicine and Traditional Chinese Medicine. Her career trajectory includes significant roles at esteemed institutions such as Shandong University of Traditional Chinese Medicine and Fudan University. Currently serving as a postdoctoral researcher at the Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Dr. Cao has demonstrated her expertise in both clinical practice and research. Her professional journey is characterized by a relentless pursuit of excellence in patient care, coupled with a commitment to advancing the frontiers of medical knowledge through scholarly inquiry and scientific investigation. Dr. Cao’s contributions to the field underscore her dedication to improving women’s health outcomes and her role as a respected authority in the intersection of modern and traditional medical practices.

Research Interest

Dr. Xianling Cao’s research interests lie at the intersection of Obstetrics and Gynecology, with a particular focus on Placental Dysfunction Disorders and interventions utilizing Traditional Chinese Medicine (TCM). She is deeply committed to unraveling the complexities surrounding reproductive health, with an emphasis on understanding the pathophysiology of placental dysfunction and exploring innovative therapeutic strategies rooted in TCM principles. Dr. Cao’s research endeavors aim to shed light on the underlying mechanisms of reproductive disorders, such as preterm birth and infertility, and to develop novel approaches for their management and treatment. By integrating modern scientific methodologies with the rich knowledge base of TCM, she seeks to bridge the gap between conventional and complementary medicine, ultimately enhancing the quality of care for women worldwide. Dr. Cao’s passion for research is fueled by a profound sense of purpose to make meaningful contributions to the field and improve patient outcomes through evidence-based practice and innovation.

Award and Honors

Dr. Xianling Cao has garnered notable recognition and accolades for her exemplary contributions to the field of Obstetrics and Gynecology, particularly in the realm of reproductive medicine and Traditional Chinese Medicine (TCM). Her outstanding achievements have earned her prestigious awards and honors, acknowledging her significant impact on advancing scientific knowledge and clinical practice in the field. Dr. Cao’s dedication to excellence, coupled with her innovative research initiatives and scholarly contributions, has consistently distinguished her as a leading figure in her field. These awards serve as a testament to her unwavering commitment to advancing women’s health and pioneering novel approaches to address reproductive health challenges.

Research Skills

Dr. Xianling Cao possesses a robust set of research skills honed through years of dedicated academic and professional pursuits. Her expertise spans various facets of research methodology, including study design, data collection, statistical analysis, and interpretation of findings. Proficient in both quantitative and qualitative research approaches, Dr. Cao demonstrates exceptional competence in conducting systematic literature reviews, meta-analyses, and clinical trials. Moreover, her adeptness in utilizing advanced research tools and technologies facilitates the exploration of complex research questions and the generation of meaningful insights. Dr. Cao’s proficiency in scientific writing and communication further enhances her ability to disseminate research findings effectively through peer-reviewed publications, presentations, and academic forums. With a keen eye for detail and a commitment to methodological rigor, she consistently upholds the highest standards of scientific inquiry, contributing to the advancement of knowledge in her field.

Publications

  • Parental mosaicism detection and preimplantation genetic testing in families with multiple transmissions of de novo mutations
    • Authors: N. Xu, W. Shi, X. Cao, S. Chen, C. Xu
    • Journal: Journal of Medical Genetics, 2023, 60(9), pp. 910–917
    • Citations: 2
  • Proinflammatory changes in the maternal circulation, maternal-fetal interface, and placental transcriptome in preterm birth: a comment
    • Authors: X. Cao, S. Chen, C. Xu
    • Journal: American Journal of Obstetrics and Gynecology, 2023, 228(6), pp. 763–764
    • Citations: 2
  • Preimplantation Genetic Testing (PGT) and Prenatal Diagnosis of Schaaf-Yang Syndrome: A Report of Three Families and a Research on Genotype–Phenotype Correlations
    • Authors: N. Xu, W. Shi, X. Cao, S. Chen, C. Xu
    • Journal: Journal of Clinical Medicine, 2023, 12(4), 1688
    • Citations: 1
  • Mechanism of Guilu Erxian ointment based on targeted metabolomics in intervening in vitro fertilization and embryo transfer outcome in older patients with poor ovarian response of kidney-qi deficiency type
    • Authors: Y. Ma, J. Song, X. Cao, Z. Sun
    • Journal: Frontiers in Endocrinology, 2023, 14, 1045384
    • Citations: 1
  • Integration of transcriptomics and metabolomics reveals the responses of the maternal circulation and maternal-fetal interface to LPS-induced preterm birth in mice
    • Authors: X. Cao, X. Zhou, S. Chen, C. Xu
    • Journal: Frontiers in Immunology, 2023, 14, 1213902
    • Citations: 0
  • Progress in the application of PGT in hereditary tumors
    • Authors: X. Cao, X. Zhou, S. Chen, H. Huang, C. Xu
    • Journal: China Oncology, 2022, 32(11), pp. 1037–1043
    • Citations: 0
  • Association of urinary bisphenol A concentrations with in vitro fertilisation outcomes: a systematic review and meta-analysis protocol
    • Authors: X.-L. Cao, N.-X. Xu, X.-Y. Zhou, C.-M. Xu
    • Journal: BMJ Open, 2022, 12(11), e063930
    • Citations: 0
  • Quantitative label-free proteomic analysis of human follicle fluid to identify novel candidate protein biomarker for endometriosis-associated infertility
    • Authors: X.-L. Cao, J.-Y. Song, Z.-G. Sun
    • Journal: Journal of Proteomics, 2022, 266, 104680
    • Citations: 6
  • Integrative analysis of circulating microRNAs and the placental transcriptome in recurrent pregnancy loss
    • Authors: N. Xu, X. Zhou, W. Shi, S. Chen, C. Xu
    • Journal: Frontiers in Physiology, 2022, 13, 893744
    • Citations: 5
  • Association of IL-4 and IL-10 Polymorphisms With Preterm Birth Susceptibility: A Systematic Review and Meta-Analysis
    • Authors: X.-L. Cao, X.-Y. Zhou, N.-X. Xu, S.-C. Chen, C.-M. Xu
    • Journal: Frontiers in Immunology, 2022, 13, 917383
    • Citations: 5