Posted on 11/07/202411/07/2024 by sciencefatherLeave a Comment on Roman Jerala | Synthetic Biology | Best Researcher Award 59 / 100 Powered by Rank Math SEO Prof. Roman Jerala | Synthetic Biology | Best Researcher Award Head of department at National Institute of Chemistry, Slovenia. Dr. Roman Jerala is a distinguished researcher and academic with profound expertise in synthetic biology and molecular biology. As Head of the Department of Synthetic Biology and Immunology at the National Institute of Chemistry in Ljubljana since 2002, and as a Full Professor of Biochemistry and Molecular Biology at the University of Ljubljana since 2010, he has made significant contributions to these fields. Dr. Jerala is renowned for his pioneering work in protein engineering, particularly in developing coiled-coil protein origami structures, and for advancing molecular modeling and computational biology techniques. His research spans diverse areas including structural biology, protein-protein interactions, and cellular signaling, critical for innovations in gene and cell therapy. With over 230 publications and numerous awards, including an ERC Advanced Grant and memberships in prestigious scientific societies, Dr. Jerala’s leadership and expertise continue to drive advancements at the interface of biology and technology, making profound impacts on the understanding and application of biological systems. Professional Profiles: Scopus Profile Google Scholar ORCID Profile Education 🎓 Prof. Dr. Roman Jerala is a distinguished researcher and academic with extensive expertise in biochemistry and molecular biology. He earned his Ph.D. in Biochemistry and Molecular Biology from the Jožef Stefan Institute (JSI) in Ljubljana, Slovenia, in 1993. Prior to this, he completed his BSc in Chemistry at the Faculty of Chemistry and Chemical Technology, University of Ljubljana, Slovenia, in 1988. These educational achievements laid the groundwork for his illustrious career focused on synthetic biology and immunology. Currently serving as the Head of the Department of Synthetic Biology and Immunology at the National Institute of Chemistry (NIC) in Ljubljana, and as a Full Professor of Biochemistry and Molecular Biology at the University of Ljubljana, Prof. Jerala continues to lead groundbreaking research initiatives and contribute significantly to the field through his innovative work in protein design and molecular regulation. Professional Experience Dr. Roman Jerala occupies pivotal roles in Slovenia’s academic and research sectors. Since 2002, he has served as the Head of the Department of Synthetic Biology and Immunology at the National Institute of Chemistry (NIC) in Ljubljana. In this capacity, Dr. Jerala spearheads innovative research endeavors, particularly in synthetic biology and immunological studies, fostering interdisciplinary collaborations and pushing the boundaries of scientific discovery. Concurrently, since 2010, he has held the position of Full Professor of Biochemistry and Molecular Biology at the University of Ljubljana. Here, he plays a crucial role in shaping the next generation of scientists, imparting knowledge, and guiding students in groundbreaking research pursuits in molecular biology. Dr. Jerala’s dual leadership roles underscore his profound impact on academia, where his research and educational contributions continue to influence the fields of synthetic biology and molecular biology, both nationally and internationally. His work exemplifies a dedication to advancing scientific understanding and application in complex biological systems. Research Interest Dr. Roman Jerala’s research interests span across synthetic biology, molecular immunology, and biochemistry, focusing on innovative approaches to biological systems and their applications. He explores the design and construction of novel biomolecular tools and systems, particularly in the realm of synthetic biology, aiming to engineer biological entities for therapeutic and biotechnological purposes. His work includes the development of protein-based nanomaterials, such as coiled-coil protein origami, and the design of synthetic gene circuits for controlling cellular processes. Dr. Jerala’s research also delves into molecular immunology, investigating immune responses and developing strategies for immunotherapy. His interdisciplinary approach integrates biochemistry, molecular biology, and computational modeling to address fundamental questions in biology and to create new technologies with potential clinical applications. Award and Honors Dr. Roman Jerala, a distinguished scientist, holds key positions in academia and research. As Head of the Department of Synthetic Biology and Immunology at the National Institute of Chemistry (NIC) in Ljubljana since 2002, and as a Full Professor of Biochemistry and Molecular Biology at the University of Ljubljana since 2010, he exemplifies leadership in advancing scientific frontiers. His research interests span synthetic biology, molecular immunology, and biochemistry, focusing on innovative approaches like coiled-coil protein origami and mammalian synthetic biology tools. Dr. Jerala’s contributions have garnered significant recognition, including an ERC Advanced Grant in 2018, the Datta Prize by FEBS in 2021, and election to prestigious bodies like the Slovenian Academy of Sciences and Arts and EMBO. His achievements extend to numerous accolades from international forums and his role in fostering scientific advancements through groundbreaking research and leadership in scientific societies and editorial boards, highlighting his profound impact on the field of molecular biology and beyond. Research Skills Dr. Roman Jerala possesses advanced research skills honed through decades of pioneering work in molecular biology and synthetic biology. His expertise includes protein engineering, particularly in the design and construction of coiled-coil protein origami structures. He is adept in structural biology techniques such as SAXS and EM for protein characterization, as well as high-resolution crystallography. Dr. Jerala’s research involves extensive use of molecular modeling and computational biology to design novel protein assemblies and regulatory systems. He is proficient in cellular and molecular techniques for studying protein-protein interactions and cellular signaling pathways, crucial for his developments in mammalian synthetic biology. His interdisciplinary approach integrates principles from bioinformatics, biophysics, and chemistry, facilitating the creation of innovative tools for gene and cell therapy applications. Dr. Jerala’s research skills are underscored by his prolific publication record and extensive collaborations with leading international researchers, reflecting his leadership in advancing the frontiers of biological sciences through cutting-edge research methodologies. Publications Mechanism of endosomal TLR inhibition by antimalarial drugs and imidazoquinolines Authors: A Kužnik, M Benčina, U Švajger, M Jeras, B Rozman, R Jerala Year: 2011 Citations: 683 The refined 2.4 AX‐ray crystal structure of recombinant human stefin B in complex with the cysteine proteinase papain: a novel type of proteinase inhibitor interaction Authors: MT Stubbs, B Laber, W Bode, R Huber, R Jerala, B Lenarcic, V Turk Year: 1990 Citations: 599 Characterization of quercetin binding site on DNA gyrase Authors: A Plaper, M Golob, I Hafner, M Oblak, T Šolmajer, R Jerala Year: 2003 Citations: 422 Structural biology of the LPS recognition Author: R Jerala Year: 2007 Citations: 413 Design of a single-chain polypeptide tetrahedron assembled from coiled-coil segments Authors: H Gradišar, S Božič, T Doles, D Vengust, I Hafner-Bratkovič, A Mertelj, R Jerala Year: 2013 Citations: 347 Similarities and Specificities of Fungal Keratinolytic Proteases: Comparison of Keratinases of Paecilomyces marquandii and Doratomyces microsporus to Some … Authors: H Gradišar, J Friedrich, I Krizaj, R Jerala Year: 2005 Citations: 315 Green tea catechins inhibit bacterial DNA gyrase by interaction with its ATP binding site Authors: H Gradišar, P Pristovšek, A Plaper, R Jerala Year: 2007 Citations: 305 DNA-guided assembly of biosynthetic pathways promotes improved catalytic efficiency Authors: RJ Conrado, GC Wu, JT Boock, H Xu, SY Chen, T Lebar, J Turnšek, R Jerala Year: 2012 Citations: 301 Chemistry of lipid A: at the heart of innate immunity Authors: A Molinaro, O Holst, F Di Lorenzo, M Callaghan, A Nurisso, G D’Errico, R Jerala Year: 2015 Citations: 261 Three-dimensional domain swapping in the folded and molten-globule states of cystatins, an amyloid-forming structural superfamily Authors: RA Staniforth, S Giannini, LD Higgins, MJ Conroy, AM Hounslow, R Jerala Year: 2001 Citations: 246 Primary structure of a new cysteine proteinase inhibitor from pig leucocytes Authors: A Ritonja, M Kopitar, R Jerala, V Turk Year: 1989 Citations: 202 The POM monoclonals: a comprehensive set of antibodies to non-overlapping prion protein epitopes Authors: M Polymenidou, R Moos, M Scott, C Sigurdson, Y Shi, B Yajima, R Jerala Year: 2008 Citations: 194 Toll‐like receptor 4 activation in cancer progression and therapy Authors: A Oblak, R Jerala Year: 2011 Citations: 187 Roman Jerala | Synthetic Biology | Best Researcher Award