Avat Arman Taherpour | Medicinal Chemistry | Best Researcher Award

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Prof Dr. Avat Arman Taherpour | Medicinal Chemistry | Best Researcher Award

Professor at Al-Balqa Applied University, Jordan

Avat Arman Taherpour is a distinguished Professor of Organic Chemistry at Razi University, Kermanshah, Iran, and a respected researcher at the Medical Biology Research Center, Kermanshah University of Medical Sciences. With a Ph.D. in Organic Chemistry from Islamic Azad University, Tehran, and post-doctoral experience at The University of Queensland, Australia, under Professor Curt Wentrup, he specializes in computational chemistry, organic synthesis, and nano-chemistry. Avat’s research focuses on applying quantum mechanical methods to study molecular structures and interactions, essential for advancing medicinal chemistry and nano-materials. He has authored numerous publications and holds international recognition, listed among the top 2% researchers worldwide. Beyond academia, Avat has held significant managerial roles, including President of the Elites Foundation in Kermanshah Province, Iran, emphasizing his leadership in fostering scientific excellence and industry collaboration. His contributions continue to shape the fields of theoretical chemistry and organic synthesis globally.

Professional Profiles:

šŸŽ“ Education

Avat Arman Taherpour pursued his academic journey with a strong foundation in chemistry, earning a B.Sc. in Applied Chemistry from Islamic Azad University, Tehran, Iran in 1990. He continued his studies with an M.Sc. in Organic Chemistry from the same institution in 1992, further deepening his expertise in chemical sciences. Avat Arman Taherpour completed his academic trajectory with a Ph.D. in Organic Chemistry from the Islamic Azad University Science and Research Branch, Tehran, Iran, in 1998. His educational background provided him with a robust theoretical framework and practical skills essential for his subsequent research and professional endeavors in the field of organic chemistry.

Ā Professional Experience

Avat Arman Taherpour is a distinguished Professor of Organic Chemistry at Razi University, Kermanshah, Iran, where he also serves as an invited researcher at the Medical Biology Research Center, Kermanshah University of Medical Sciences. With a robust academic background, including a Ph.D. in Organic Chemistry and post-doctoral research at The University of Queensland, Australia, he specializes in Organic and Medicinal Chemistry, Quantum Mechanical and Computational Chemistry, and Nano-Chemistry. Avat has held significant administrative roles, such as President of the Elites Foundation for Kermanshah Province and Head of the Nano-Chemistry Department at Razi University. His career highlights include fostering industry-academia partnerships and contributing extensively to the advancement of scientific research and education in Iran.

Research Interest

Avat Arman Taherpour’s research interests encompass a wide array of fields within chemistry, focusing primarily on Organic and Medicinal Chemistry. His expertise extends to Quantum Mechanical and Computational Chemistry, Molecular Modeling, Theoretical Chemistry, and Physical Organic Chemistry. He is deeply engaged in Spectroscopic Studies of Organic Compounds and Nano-Chemistry, exploring innovative applications and theoretical frameworks. Avat’s research aims to bridge theoretical insights with practical applications, emphasizing the role of computational tools in enhancing experimental outcomes and understanding molecular interactions. His work underscores the importance of advancing chemical sciences through interdisciplinary approaches, particularly in areas like biochemistry, nano-systems, and medicinal chemistry, thereby contributing to both theoretical advancements and practical innovations in the field.

Award and Honors

Avat Arman Taherpour has been recognized internationally for his contributions to the field of chemistry, notably being listed among the top 2% researchers worldwide in all fields in 2019, 2020, and 2021. This prestigious recognition underscores his significant impact and scholarly contributions to scientific research. His achievements reflect his dedication to advancing knowledge in Organic and Medicinal Chemistry, Quantum Mechanical and Computational Chemistry, and Nano-Chemistry. Avat’s commitment to excellence in research and his innovative approaches have earned him acclaim within the global scientific community, highlighting his influential role in pushing the boundaries of chemical sciences

Research Skills

Avat Arman Taherpour is a distinguished researcher with a profound expertise in various domains of chemistry. His research skills encompass computational chemistry, where he applies advanced quantum mechanical methods to explore molecular structures and interactions, particularly in organic and medicinal chemistry. He is adept at organic synthesis, having designed and synthesized intricate compounds pivotal for drug development. Utilizing spectroscopic techniques such as NMR, IR, and UV spectroscopy, Avat characterizes organic and medicinal compounds with precision, elucidating their structural properties. His proficiency extends to nano-chemistry, where he investigates nano-scale materials for diverse applications in chemical sciences. Additionally, Avat’s knowledge in physical organic chemistry enables him to delve into reaction mechanisms and the physical properties of organic compounds, essential for enhancing synthetic strategies and understanding chemical behaviors. His comprehensive skill set integrates theoretical insights with practical applications, positioning him as a leading figure in advancing innovative research at the intersection of chemistry disciplines.

Publications

  1. Molecular modelling of fullerene C60 functionalized by nitric oxide for use in biological environment
    • Authors: Moztarzadeh, O., Jamshidi, M., Taherpour, A.A., Babuska, V.
    • Year: 2024
    • Journal: Scientific Reports
    • Volume: 14(1)
    • Pages: 2565
  2. Nitrile Imine Cyclizations and Rearrangements: N-Phenyl-C-styrylnitrile Imine and N-Phenyl-C-phenylethynylnitrile Imine
    • Authors: Miri, M., Taherpour, A.A., Wentrup, C.
    • Year: 2024
    • Journal: Journal of Organic Chemistry
    • Volume: 89(13)
    • Pages: 9360ā€“9370
  3. Modeling of an efficient donor-Ļ€-acceptor-Ļ€ organic solar cell: a first principle study of a holeā€“electron process by DFT and TD-DFT study
    • Authors: Hassani Daramroudi, A., Taherpour, A.A., Jamshidi, M.
    • Year: 2024
    • Journal: Journal of the Iranian Chemical Society
    • Volume: 21(5)
    • Pages: 1353ā€“1368
  4. Ni0.5Co0.5WO4@f-MWCNTs/GO nanocomposite with improved supercapattery activity as the electrode for asymmetric supercapacitor device
    • Authors: Abdolahi, B., Gholivand, M.B., Shamsipur, M., Mirzaei, M., Daramroudi, A.H., Taherpour, A.A.
    • Year: 2023
    • Journal: Journal of Energy Storage
    • Volume: 73
    • Pages: 109181
    • Citations: 9
  5. Experimental and computational investigation of multi-walled carbon nanotubes decorated by Coā€“Niā€“Se@MoSe2 coreā€“shell as a sustainable counter electrode for dye-sensitized solar cells
    • Authors: Norouzibazaz, M., Gholivand, M.B., Taherpour, A.A., Mirzaei, M.
    • Year: 2023
    • Journal: Materials Today Energy
    • Volume: 38
    • Pages: 101447
    • Citations: 5
  6. Corrigendum to: Synthesis and Application of Nano Vanadium-Oxo Pyridiniumporphyrazinato Sulfonic Acid for Synthesizing Pyrazole and Dihydropyrano [2,3] pyrazole Derivatives
    • Authors: Moeinimehr, M., Safaiee, M., Zolfigol, M.A., Taherpour, A.A.
    • Year: 2023
    • Journal: ChemistrySelect
    • Volume: 8(16)
    • Pages: e202204422
  7. Zwitterionic hydrogen-bonded organic framework (ZHOF): a metal-free water oxidation proton relay in alkaline and neutral media
    • Authors: Azizi, R., Shamsipur, M., Taherpour, A., Pashabadi, A.
    • Year: 2023
    • Journal: Journal of Materials Chemistry A
    • Volume: 11(3)
    • Pages: 1491ā€“1502
    • Citations: 7
  8. Catalytic synergism in Mn-heterostructured molybdenum oxysulfide hybridized with transition metal phosphides: A robust amorphous water oxidation catalyst
    • Authors: Ahanjan, K., Shamsipur, M., Taherpour, A., Pashabadi, A.
    • Year: 2022
    • Journal: Electrochimica Acta
    • Volume: 433
    • Pages: 141249
    • Citations: 4
  9. An ideal ratiometric fluorescent probe provided by the surface modification of carbon dots for the determination of Pb2+
    • Authors: Paydar, S., Feizi, F., Shamsipur, M., Taherpour, A.A., Jamshidi, M.
    • Year: 2022
    • Journal: Sensors and Actuators B: Chemical
    • Volume: 369
    • Pages: 132243
    • Citations: 23
  10. Retraction: Experimental and theoretical studies of the nanostructured {Fe3O4@SiO2@(CH2)3Im}C(CN)3 catalyst for 2-amino-3-cyanopyridine preparation via an anomeric based oxidation
    • Authors: Zolfigol, M.A., Kiafar, M., Yarie, M., Taherpour, A., Saeidi-Rad, M.
    • Year: 2022
    • Journal: RSC Advances
    • Volume: 12(42)
    • Pages: 27114

 

 

Seyedeh Hoda Alavizadeh | Pharmaceutical Science | Best Researcher Award

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Assist Prof Dr. Seyedeh Hoda Alavizadeh | Pharmaceutical Science | Best Researcher Award

Assistant professor at Pharmaceutical Nanotechnology Department, School of Pharmacy, Mashhad University of Medical Sciences, Iran.

Seyedeh Hoda Alavizadeh is an accomplished assistant professor in pharmaceutical nanotechnology at Mashhad University of Medical Sciences, Iran. Her research focuses on innovative drug delivery systems, particularly liposomal formulations for targeted cancer therapy and neurodegenerative diseases. She has a strong academic background with a Pharm.D. and Ph.D. from MUMS, along with numerous honors including fellowships, grants, and awards like being recognized in the top 1% worldwide for her research. Her leadership extends to organizing international conferences and serving as a CRS ambassador. Alavizadeh’s contributions to pharmaceutical sciences are marked by her extensive publication record and active role in international collaborations and editorial activities.

Professional Profiles:

Education šŸŽ“

Seyedeh Hoda Alavizadeh completed her Ph.D. in Pharmaceutical Nanotechnology at the School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran. Her doctoral research focused on the formulation and characterization of temperature-sensitive nanoliposomal cisplatin targeted with anti-Her-2/neu affibody, investigating its antitumor effects with local hyperthermia in vitro and in vivo using mouse tumor models. Under the guidance of Prof. Mahmoud Reza Jaafari, her work contributed significantly to understanding drug delivery mechanisms in cancer treatment. Prior to her Ph.D., she obtained her Pharm. D. from the same institution, specializing in vaccine delivery against leishmaniasis, supervised by Prof. Ali Khamesipour, Prof. Mahmoud Reza Jaafari, and Dr. Ali Badiee. Her Pharm. D. thesis focused on evaluating immune responses in mice inoculated with L. major mixed with LPD nanoparticles containing CpG ODN, demonstrating her early commitment to innovative pharmaceutical research.

Professional Experience

Since completing her education, Seyedeh Hoda Alavizadeh has served as an Assistant Professor at the Pharmaceutical Nanotechnology Department, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran. Her interdisciplinary research is grounded in innovation and quality, focusing on developing tumor microenvironment-responsive liposomes for anti-cancer drug delivery. Her expertise includes the formulation of triggered-release liposomesā€”such as thermo, REDOX, and pH-sensitive formulationsā€”tailored to the tumor microenvironment for cancer therapy and chemo-immunotherapy. She has been actively involved in teaching courses on pharmacy practice, basic biochemistry, biology, cell culture, and advanced topics in drug delivery using nanoparticles.

Research Interest

Seyedeh Hoda Alavizadeh’s research interests are centered on pharmaceutical nanotechnology, with a focus on developing advanced liposomal formulations for targeted drug delivery in cancer therapy. Her research explores triggered-release systems responsive to the tumor microenvironment, including thermo-sensitive, REDOX-sensitive, and pH-sensitive formulations. She is particularly interested in enhancing the efficacy of chemotherapy through innovative liposomal designs and investigating their applications in chemo-immunotherapy. Additionally, she is passionate about developing liposomal formulations of phytochemicals for their antioxidant and neuroprotective roles in diseases like Alzheimer’s and Parkinson’s, contributing to advancements in nanomedicine for therapeutic interventions.

Award and Honors

Seyedeh Hoda Alavizadeh has been recognized with several prestigious honors and awards throughout her career. She served as a CRS Ambassador from 2021 to 2023, promoting excellence in controlled release science. In 2020, she was awarded the Fellowship of the CLINAM Conference and Exhibition, held in Basel, Switzerland, highlighting her contributions to nanomedicine research. Her academic pursuits were further supported by the DAAD Scholarship for the ProGRANT proposal writing course in 2018 and the NIMAD research grant in the same year. Notably, she received the Best Poster Presentation Award at the CLINAM10th Conference and Exhibition in 2017 and was also honored with a Fellowship at the same event, recognizing her impactful research contributions. In 2016, her work was distinguished globally, ranking in the top 1% of papers by Essential Science Indicator of Thomson Reuters ISI, underscoring her significant scholarly impact.

Research Skills

Seyedeh Hoda Alavizadeh possesses a robust skill set in pharmaceutical nanotechnology, focusing on advanced drug delivery systems. Her expertise spans the development of liposomal formulations tailored for targeted delivery of chemotherapeutic agents and phytochemicals, leveraging innovative strategies such as thermo-responsive, REDOX-sensitive, and pH-sensitive mechanisms to optimize drug efficacy while minimizing adverse effects. With a comprehensive understanding of biochemical assays, she proficiently evaluates drug encapsulation efficiencies, release kinetics, and therapeutic outcomes in experimental models. Her academic leadership is evident through roles like vice-scientific chair for the ICNN2021 conference, underscoring her organizational acumen and commitment to advancing nanoscience and nanotechnology. Additionally, her active involvement in international collaborations and editorial responsibilities showcases her dedication to peer-reviewed research and scientific excellence in pharmaceutics and nanomedicine.

Publications

  • Bioactivity assessment and toxicity of crocin: a comprehensive review
    • Authors: SH Alavizadeh, H Hosseinzadeh
    • Year: 2014
    • Citations: 422
  • Novel nanomicelle formulation to enhance bioavailability and stability of curcuminoids
    • Authors: M Hatamipour, A Sahebkar, SH Alavizadeh, M Dorri, MR Jaafari
    • Year: 2019
    • Citations: 102
  • Antitumor activity of PEGylated nanoliposomes containing crocin in mice bearing C26 colon carcinoma
    • Authors: M Rastgoo, H Hosseinzadeh, H Alavizadeh, A Abbasi, Z Ayati, MR Jaafari
    • Year: 2013
    • Citations: 90
  • Redox-sensitive nanoscale drug delivery systems for cancer treatment
    • Authors: E Mirhadi, M Mashreghi, MF Maleki, SH Alavizadeh, L Arabi, A Badiee, …
    • Year: 2020
    • Citations: 80
  • Induction of protection against leishmaniasis in susceptible BALB/c mice using simple DOTAP cationic nanoliposomes containing soluble Leishmania antigen (SLA)
    • Authors: H Firouzmand, A Badiee, A Khamesipour, VH Shargh, SH Alavizadeh, …
    • Year: 2013
    • Citations: 63
  • Improved therapeutic activity of HER2 Affibody-targeted cisplatin liposomes in HER2-expressing breast tumor models
    • Authors: SH Alavizadeh, J Akhtari, A Badiee, S Golmohammadzadeh, MR Jaafari
    • Year: 2016
    • Citations: 56
  • Targeting, biodistribution and tumor growth inhibiting characterization of anti-HER2 affibody coupling to liposomal doxorubicin using BALB/c mice bearing TUBO tumors
    • Authors: J Akhtari, SM Rezayat, M Teymouri, SH Alavizadeh, F Gheybi, A Badiee, …
    • Year: 2016
    • Citations: 48
  • Development of a topical liposomal formulation of Amphotericin B for the treatment of cutaneous leishmaniasis
    • Authors: MR Jaafari, M Hatamipour, SH Alavizadeh, A Abbasi, Z Saberi, S Rafati, …
    • Year: 2019
    • Citations: 46
  • The influence of phospholipid on the physicochemical properties and anti-tumor efficacy of liposomes encapsulating cisplatin in mice bearing C26 colon carcinoma
    • Authors: SH Alavizadeh, A Badiee, S Golmohammadzadeh, MR Jaafari
    • Year: 2014
    • Citations: 46
  • Development of topical liposomes containing miltefosine for the treatment of Leishmania major infection in susceptible BALB/c mice
    • Authors: Z Kavian, SH Alavizadeh, S Golmohamadzadeh, A Badiee, …
    • Year: 2019
    • Citations: 40
  • The molecular mechanisms of curcuminā€™s inhibitory effects on cancer stem cells
    • Authors: E Zendehdel, E Abdollahi, AA Momtaziā€Borojeni, M Korani, …
    • Year: 2019
    • Citations: 34