Pratiksha Kshirsagar | Pre-clinical pharmacology | Best Researcher Award | 13450

Published on by Research Awards

Ms. Pratiksha Kshirsagar | Pre-clinical pharmacology | Best Researcher Award

Ms. Pratiksha Kshirsagar, University of Nebraska Medical Center, United States

Ms. Pratiksha Kshirsagar is a dedicated pharmaceutical scientist currently pursuing her Ph.D. in Pharmaceutical Sciences at the University of Nebraska Medical Center (UNMC), USA. With strong academic credentials and hands-on research experience in both India and the U.S., she specializes in bioanalytical method development, preclinical pharmacokinetics, and drug delivery systems. Her work includes the development and validation of LC-MS/MS methods and conducting in vitro and in vivo DMPK studies for novel therapeutics targeting medulloblastoma. She has co-authored several peer-reviewed publications and presented her findings at national and international conferences. Ms. Kshirsagar is also a recipient of the UNMC Dean of Graduate Studies Conference Attendance Award and remains committed to advancing pharmaceutical research and translational drug development.

Profile

ORCID

🎓 Early Academic Pursuits

Pratiksha Kshirsagar’s academic journey is marked by consistent dedication and a keen interest in pharmaceutical sciences. Her educational foundation was laid at Savitribai Phule Pune University, where she earned both her Bachelor of Pharmacy (2016–2020) with an SGPA of 7.7/10 and a Master of Pharmacy in Pharmaceutics (2020–2022), graduating with distinction (SGPA: 8.96/10). These formative years laid the groundwork for her strong research acumen and laboratory skills. Keen to explore further, she transitioned to the University of Nebraska Medical Center (UNMC), USA, where she pursued a Master of Pharmaceutical Sciences (2022–2024). Her academic growth culminated in her enrollment in the Ph.D. program in Pharmaceutical Sciences (2024–2029). With a GPA of 3.6/4.0, her progress has been both steady and impressive. Simultaneously, she earned a Certificate in Applied Biostatistics with a perfect GPA of 4.0/4.0, showcasing her commitment to interdisciplinary learning and data-driven research.

🧪 Professional Endeavors

Pratiksha’s professional experience is deeply intertwined with her academic path, reflecting a rare blend of scholarly rigor and hands-on application. At UNMC, under the mentorship of Dr. Daryl J. Murry, she has worked extensively as a graduate research assistant and student researcher, contributing to the development and validation of LC-MS/MS bioanalytical methods for novel small molecules and RIPTACs. Her earlier professional journey in India involved impactful research under Dr. Smita S. Pimple, where she explored micro-emulsions using essential oils and carrier oils for skincare applications. This early exposure to formulation science, coupled with analytical chemistry, gave her a solid foundation in pharmaceutics and laboratory research.

🔬 Contributions and Research Focus

Pratiksha’s primary research focus lies in drug metabolism and pharmacokinetics (DMPK), with an emphasis on preclinical evaluation of novel therapeutic agents. Her notable contributions include the in-depth pharmacokinetic analysis of EPZ015666 and JNJ-64619178 for medulloblastoma treatment, reflecting her role in advancing pediatric cancer therapy.

Her technical expertise spans several key areas:

  • LC-MS/MS bioanalytical method development

  • In-vitro studies like metabolic stability, protein binding, and drug transporter assays

  • In-vivo animal studies, including oral/IV dosing and tissue distribution

  • Use of Phoenix WinNonlin, GraphPad Prism, and other analytical tools for pharmacokinetic modeling

Moreover, she contributed to the design, characterization, and stability testing of advanced nano drug delivery systems such as S-SNEDDS (Solid Self-Nanoemulsifying Drug Delivery System), which demonstrates her interdisciplinary knowledge.

🏅 Accolades and Recognition

Pratiksha’s dedication has earned her notable recognition throughout her academic and research journey. She was awarded the UNMC Dean of Graduate Studies Conference Attendance Award in 2023, underscoring her academic excellence and potential for contribution at scientific forums.

She actively participated in esteemed conferences such as:

  • American Association of Pharmaceutical Scientists (AAPS), Oct 2023

  • UNMC College of Pharmacy Research Day, May 2023

  • CHRI Pediatric Research Forum, May 2023

In earlier academic years, she was involved in state and national level conferences and poster competitions, including the Medical Coding & E-Poster Competition (2020) and a State Level Seminar on Natural Products Research (2018).

🌍 Impact and Influence

Pratiksha’s research holds real-world significance. Her work on small molecule therapeutics for medulloblastoma contributes to the body of knowledge addressing rare pediatric brain cancers, potentially guiding future clinical interventions. Her cross-functional approach—merging analytical chemistry, pharmacology, and pharmaceutical formulation—makes her an invaluable contributor to translational medicine. She has also co-authored several scholarly publications and book chapters on nanotechnology, drug delivery, and antiviral drug challenges, reinforcing her growing influence in the academic community. These contributions are cited in peer-reviewed journals and academic textbooks, evidencing her thought leadership.

đź”® Legacy and Future Contributions

As Pratiksha continues her Ph.D. journey, her trajectory suggests a future as a leading scientist in pharmaceutical research and drug development. Her interests align with solving complex challenges in drug delivery, pharmacokinetics, and personalized medicine. Looking ahead, she aims to bridge the gap between bench-side research and bedside applications, translating scientific breakthroughs into therapeutic realities. Whether in academia, industry, or clinical collaborations, her vision is clear: to contribute meaningfully to global health innovation.

đź“„ Publication Top Notes

Crossing the Blood–Brain Barrier: Innovations in Receptor- and Transporter-Mediated Transcytosis Strategies

Contributors: Ling Ding; Pratiksha Kshirsagar; Prachi Agrawal; Daryl J. Murry

Journal: Pharmaceutics

Year: 2025

Preparation and Characterization of Advanced Nano medicine For Malaria: Box Behnken Design Approach

Contributors: Anuradha G. More; Parag R. Potbhare; Padmaja S. Kore; Praveen D. Chaudhari; Pratiksha U. Kshirsagar; Radhika R. Baheti; Surbhi C. Gupta

Journal: International Journal of Life Science and Pharma Research

Year: 2022

Avat Arman Taherpour | Medicinal Chemistry | Best Researcher Award

Published on by Research Awards

Prof Dr. Avat Arman Taherpour | Medicinal Chemistry | Best Researcher Award

Professor at Al-Balqa Applied University, Jordan

Avat Arman Taherpour is a distinguished Professor of Organic Chemistry at Razi University, Kermanshah, Iran, and a respected researcher at the Medical Biology Research Center, Kermanshah University of Medical Sciences. With a Ph.D. in Organic Chemistry from Islamic Azad University, Tehran, and post-doctoral experience at The University of Queensland, Australia, under Professor Curt Wentrup, he specializes in computational chemistry, organic synthesis, and nano-chemistry. Avat’s research focuses on applying quantum mechanical methods to study molecular structures and interactions, essential for advancing medicinal chemistry and nano-materials. He has authored numerous publications and holds international recognition, listed among the top 2% researchers worldwide. Beyond academia, Avat has held significant managerial roles, including President of the Elites Foundation in Kermanshah Province, Iran, emphasizing his leadership in fostering scientific excellence and industry collaboration. His contributions continue to shape the fields of theoretical chemistry and organic synthesis globally.

Professional Profiles:

🎓 Education

Avat Arman Taherpour pursued his academic journey with a strong foundation in chemistry, earning a B.Sc. in Applied Chemistry from Islamic Azad University, Tehran, Iran in 1990. He continued his studies with an M.Sc. in Organic Chemistry from the same institution in 1992, further deepening his expertise in chemical sciences. Avat Arman Taherpour completed his academic trajectory with a Ph.D. in Organic Chemistry from the Islamic Azad University Science and Research Branch, Tehran, Iran, in 1998. His educational background provided him with a robust theoretical framework and practical skills essential for his subsequent research and professional endeavors in the field of organic chemistry.

 Professional Experience

Avat Arman Taherpour is a distinguished Professor of Organic Chemistry at Razi University, Kermanshah, Iran, where he also serves as an invited researcher at the Medical Biology Research Center, Kermanshah University of Medical Sciences. With a robust academic background, including a Ph.D. in Organic Chemistry and post-doctoral research at The University of Queensland, Australia, he specializes in Organic and Medicinal Chemistry, Quantum Mechanical and Computational Chemistry, and Nano-Chemistry. Avat has held significant administrative roles, such as President of the Elites Foundation for Kermanshah Province and Head of the Nano-Chemistry Department at Razi University. His career highlights include fostering industry-academia partnerships and contributing extensively to the advancement of scientific research and education in Iran.

Research Interest

Avat Arman Taherpour’s research interests encompass a wide array of fields within chemistry, focusing primarily on Organic and Medicinal Chemistry. His expertise extends to Quantum Mechanical and Computational Chemistry, Molecular Modeling, Theoretical Chemistry, and Physical Organic Chemistry. He is deeply engaged in Spectroscopic Studies of Organic Compounds and Nano-Chemistry, exploring innovative applications and theoretical frameworks. Avat’s research aims to bridge theoretical insights with practical applications, emphasizing the role of computational tools in enhancing experimental outcomes and understanding molecular interactions. His work underscores the importance of advancing chemical sciences through interdisciplinary approaches, particularly in areas like biochemistry, nano-systems, and medicinal chemistry, thereby contributing to both theoretical advancements and practical innovations in the field.

Award and Honors

Avat Arman Taherpour has been recognized internationally for his contributions to the field of chemistry, notably being listed among the top 2% researchers worldwide in all fields in 2019, 2020, and 2021. This prestigious recognition underscores his significant impact and scholarly contributions to scientific research. His achievements reflect his dedication to advancing knowledge in Organic and Medicinal Chemistry, Quantum Mechanical and Computational Chemistry, and Nano-Chemistry. Avat’s commitment to excellence in research and his innovative approaches have earned him acclaim within the global scientific community, highlighting his influential role in pushing the boundaries of chemical sciences

Research Skills

Avat Arman Taherpour is a distinguished researcher with a profound expertise in various domains of chemistry. His research skills encompass computational chemistry, where he applies advanced quantum mechanical methods to explore molecular structures and interactions, particularly in organic and medicinal chemistry. He is adept at organic synthesis, having designed and synthesized intricate compounds pivotal for drug development. Utilizing spectroscopic techniques such as NMR, IR, and UV spectroscopy, Avat characterizes organic and medicinal compounds with precision, elucidating their structural properties. His proficiency extends to nano-chemistry, where he investigates nano-scale materials for diverse applications in chemical sciences. Additionally, Avat’s knowledge in physical organic chemistry enables him to delve into reaction mechanisms and the physical properties of organic compounds, essential for enhancing synthetic strategies and understanding chemical behaviors. His comprehensive skill set integrates theoretical insights with practical applications, positioning him as a leading figure in advancing innovative research at the intersection of chemistry disciplines.

Publications

  1. Molecular modelling of fullerene C60 functionalized by nitric oxide for use in biological environment
    • Authors: Moztarzadeh, O., Jamshidi, M., Taherpour, A.A., Babuska, V.
    • Year: 2024
    • Journal: Scientific Reports
    • Volume: 14(1)
    • Pages: 2565
  2. Nitrile Imine Cyclizations and Rearrangements: N-Phenyl-C-styrylnitrile Imine and N-Phenyl-C-phenylethynylnitrile Imine
    • Authors: Miri, M., Taherpour, A.A., Wentrup, C.
    • Year: 2024
    • Journal: Journal of Organic Chemistry
    • Volume: 89(13)
    • Pages: 9360–9370
  3. Modeling of an efficient donor-π-acceptor-π organic solar cell: a first principle study of a hole–electron process by DFT and TD-DFT study
    • Authors: Hassani Daramroudi, A., Taherpour, A.A., Jamshidi, M.
    • Year: 2024
    • Journal: Journal of the Iranian Chemical Society
    • Volume: 21(5)
    • Pages: 1353–1368
  4. Ni0.5Co0.5WO4@f-MWCNTs/GO nanocomposite with improved supercapattery activity as the electrode for asymmetric supercapacitor device
    • Authors: Abdolahi, B., Gholivand, M.B., Shamsipur, M., Mirzaei, M., Daramroudi, A.H., Taherpour, A.A.
    • Year: 2023
    • Journal: Journal of Energy Storage
    • Volume: 73
    • Pages: 109181
    • Citations: 9
  5. Experimental and computational investigation of multi-walled carbon nanotubes decorated by Co–Ni–Se@MoSe2 core–shell as a sustainable counter electrode for dye-sensitized solar cells
    • Authors: Norouzibazaz, M., Gholivand, M.B., Taherpour, A.A., Mirzaei, M.
    • Year: 2023
    • Journal: Materials Today Energy
    • Volume: 38
    • Pages: 101447
    • Citations: 5
  6. Corrigendum to: Synthesis and Application of Nano Vanadium-Oxo Pyridiniumporphyrazinato Sulfonic Acid for Synthesizing Pyrazole and Dihydropyrano [2,3] pyrazole Derivatives
    • Authors: Moeinimehr, M., Safaiee, M., Zolfigol, M.A., Taherpour, A.A.
    • Year: 2023
    • Journal: ChemistrySelect
    • Volume: 8(16)
    • Pages: e202204422
  7. Zwitterionic hydrogen-bonded organic framework (ZHOF): a metal-free water oxidation proton relay in alkaline and neutral media
    • Authors: Azizi, R., Shamsipur, M., Taherpour, A., Pashabadi, A.
    • Year: 2023
    • Journal: Journal of Materials Chemistry A
    • Volume: 11(3)
    • Pages: 1491–1502
    • Citations: 7
  8. Catalytic synergism in Mn-heterostructured molybdenum oxysulfide hybridized with transition metal phosphides: A robust amorphous water oxidation catalyst
    • Authors: Ahanjan, K., Shamsipur, M., Taherpour, A., Pashabadi, A.
    • Year: 2022
    • Journal: Electrochimica Acta
    • Volume: 433
    • Pages: 141249
    • Citations: 4
  9. An ideal ratiometric fluorescent probe provided by the surface modification of carbon dots for the determination of Pb2+
    • Authors: Paydar, S., Feizi, F., Shamsipur, M., Taherpour, A.A., Jamshidi, M.
    • Year: 2022
    • Journal: Sensors and Actuators B: Chemical
    • Volume: 369
    • Pages: 132243
    • Citations: 23
  10. Retraction: Experimental and theoretical studies of the nanostructured {Fe3O4@SiO2@(CH2)3Im}C(CN)3 catalyst for 2-amino-3-cyanopyridine preparation via an anomeric based oxidation
    • Authors: Zolfigol, M.A., Kiafar, M., Yarie, M., Taherpour, A., Saeidi-Rad, M.
    • Year: 2022
    • Journal: RSC Advances
    • Volume: 12(42)
    • Pages: 27114