Zu-Chian Chiang | Biochemistry | Best Researcher Award | 13347

Dr. Zu-Chian Chiang | Biochemistry | Best Researcher Award 

Dr. Zu-Chian Chiang, Fujian Normal University, China

Dr. Zu-Chian Chiang is a postdoctoral fellow at the Biomedical Research Center of Southern China, Fujian Normal University, China, with a rich background in materials and chemical engineering. His research contributions span antibody-drug conjugates (ADCs), functional peptide synthesis, biomaterials for regenerative medicine, and aptamer-based cancer therapy. His work has geographic impact across Taiwan and Mainland China, contributing to translational medicine and oncology through collaborative efforts with prestigious institutions like Academia Sinica and National Taiwan University. His applied research in ADCs and biomaterial scaffolds directly supports cancer treatment innovations. Notable projects include the development of CD47-targeting ADCs for non-small cell lung cancer, and thalidomide-PD1 combinations for enhanced immunotherapy. His publications in Frontiers in Oncology, PLOS ONE, and Current Pharmaceutical Biotechnology highlight his influence in drug delivery and cancer therapeutics. In the vector control domain, his scaffold research contributes to potential localized drug delivery systems. Dr. Chiang has received awards such as the Science and Technology Commissioner honor from Quanzhou and the Biotech Elite Training Award. His achievements exemplify impactful biomedical research with real-world therapeutic implications.

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🌱 Early Academic Pursuits

Dr. Zu-Chian Chiang embarked on his scientific journey with a passion for chemistry and materials science. He earned his Master’s Degree in Chemistry from Tunghai University, Taiwan (2005–2007), under the guidance of Prof. Feng-Di Lung. Building on this solid foundation, he pursued his Ph.D. in Materials and Chemical Engineering at National United University, Taiwan (2008–2014). During his doctoral studies, he was mentored by Prof. An-Chong Chao and co-advised by Dr. Guo-Chung Dong, focusing on biomaterials and nanomedicine.

Even as a student, Dr. Chiang demonstrated exceptional academic capabilities, earning scholarships and recognition for his innovative research. His academic training laid the groundwork for his future contributions in biomedical engineering and cancer therapeutics.

🧪 Professional Endeavors

Dr. Chiang has held several prestigious postdoctoral positions. His professional journey reflects a commitment to interdisciplinary collaboration and translational research:

  • Postdoctoral Fellow at the Biomedical Research Center of Southern China, Fujian Normal University (2019–Present), working under Prof. Qi Chen.

  • Postdoctoral Fellow at the Institute of Biological Chemistry, Academia Sinica, Taiwan (2016–2019), contributing to the Taiwan Protein Project (TPP) and the Technical Support Platform Spindle Project (TSPA).

  • Postdoctoral Fellow at the Clinical Trial Center, National Taiwan University Hospital (2015–2016), supported by Taiwan’s prestigious Biotech Elite Training Program.

Throughout these roles, Dr. Chiang has engaged in cutting-edge biomedical research with direct implications for drug development and clinical applications.

🔬 Contributions and Research Focus

Dr. Chiang’s research centers on innovative therapeutic materials and drug delivery systems, particularly in cancer therapy. His core interests include:

  • Antibody-Drug Conjugates (ADCs): Targeted cancer therapies such as HER2-positive and CD47-specific ADCs.

  • Functional Peptide Synthesis for bone tissue engineering and cancer inhibition.

  • Bio-Micro-Macro Molecular Materials for regenerative medicine.

  • Aptamer Development as modulators in therapeutic settings.

Notable publications include research on CD47-targeting ADCs (Frontiers in Oncology, 2022) and HER2-positive ADCs (PLOS ONE, 2020). His work on dexamethasone-immobilized chitosan scaffolds and chitosan-caffeic acid hybrids also provides valuable insights into localized drug delivery and tissue engineering.

🏆 Accolades and Recognition

Dr. Chiang’s dedication has been acknowledged through numerous awards:

  • 🥇 Science and Technology Commissioner, Quanzhou, Fujian Province (2020)

  • 🥇 Biotech Elite Training Award, National Taiwan University & Ministry of Science and Technology (2016)

  • 🥇 Chung Hwa Rotary Doctoral Program Award, Taiwan (2012)

  • 🥇 Outstanding Doctoral Scholarship, National United University (2010)

  • 🥇 Master’s Program Scholarship, Hunan Fellow Association of Taiwan (2007)

  • 🥇 Rotary Leadership Award, Miaoli Southeastern Xindong Satellite Rotary Club (2017)

These accolades affirm his position as a respected figure in the fields of biomedical chemistry and translational medicine.

🌍 Impact and Influence

Dr. Chiang’s work has made a geographic impact spanning Taiwan and Mainland China. His collaborative research in academia and clinical centers bridges the gap between laboratory research and therapeutic application. He actively contributes as a peer reviewer for the International Journal of Biological Macromolecules, influencing scientific standards and publication quality globally.

He is also engaged in community service through leadership in Rotary International, fostering science-driven community development and education.

🌟 Legacy and Future Contributions

Dr. Chiang’s legacy is being built on the foundation of scientific excellence, mentorship, and translational impact. His research not only pushes the boundaries of biomedical engineering but also aims to enhance the effectiveness of cancer treatments in clinical practice. With a commitment to developing next-generation targeted therapies and biomaterial scaffolds, Dr. Chiang is poised to shape the future of personalized medicine and regenerative technologies.

Looking ahead, he aims to establish interdisciplinary collaborations and contribute to global health initiatives, making life-saving therapies more effective and accessible.

Publication Top Notes

Development of Novel CD47-Specifific ADCs Possessing High Potency Against Non-Small Cell Lung Cancer in vitro and in vivo. 

Author: Z.C., Chiang, Zu Chian, S., Fang, Shubin, Y., Shen, Yangkun, J., Lin, Jizhen, Q., Chen, Qi

Journal: Frontiers in Oncology,

Year: 2022

Preparation and characterization of dexamethasone-immobilized chitosan scaffold

Author: Z.C., Chiang, Zu Chian, S., Yu, Shuhuei, A., Chao, Anchong, G.C., Dong, Guo Chung

Journal: Journal of Bioscience and Bioengineering, 

Year: 2012

 

Kanthlal S K | Pharmacology | Best Researcher Award | 12712

Dr. Kanthlal S K | Pharmacology | Best Researcher Award

Dr. Kanthlal S K, Amrita Vishwa Vidyapeetham, India

Dr. Kanthlal S K from Amrita Vishwa Vidyapeetham, India, emerges as an exemplary candidate for the Research for Community Impact Award. His extensive research contributions, practical applications, and collaborative efforts address significant community health and environmental issues, making him a highly deserving nominee.

Profile

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Education

Ph.D. in Pharmaceutical Sciences
  • Year of Completion: 2022
  • Institution: Amrita School of Pharmacy
  • University: Amrita Vishwa Vidyapeetham
  • Dissertation: Effect of Aqueous Extract of Large Cardamom on Experimental Models of Hypertension and Endothelium Function
M.Pharm in Pharmacology
  • Year of Completion: 2012
  • Institution: JKK Munirajah College of Pharmacy
  • University: Dr. MGR Medical University
  • Thesis: Evaluation of the Anti-Obesity Activity of Methanol Extract of Aerial Parts of Tabernaemontana divaricata in Atherogenic Diet-Induced Obesity in Rats
B.Pharm
  • Year of Completion: 2009
  • Institution: S B College of Pharmacy
  • University: Dr. MGR Medical University
  • Project: Study of In-Vitro Antioxidant and Free Radical Scavenging Activity of Alysicarpus monolifer Lin
D.Pharm
  • Year of Completion: 2005
  • Institution: NMS College, Mathar Thiruvattar
  • University: Directorate of Medical Education

Professional Experience

Current Position
  • Title: Assistant Professor
  • Institution: Amrita School of Pharmacy
  • Location: Kochi, Kerala, India
  • Duration: January 2013 – Present
Previous Research Experience
  1. Co-Investigator:
    • Project: “Effect of Large Cardamom on Experimental Models of Hypertension and Endothelial Functions in Isolated Aorta”
    • Funding: Spices Board of India
    • Duration: 2016 – 2019
    • Amount: 25 Lakhs INR
  2. Project Work:
    • Ph.D. Project: Focused on the effect of aqueous extract of large cardamom on experimental models of hypertension and endothelium function.
    • M.Pharm Project: Evaluated the anti-obesity activity of methanol extract of Tabernaemontana divaricata in rats.
    • B.Pharm Project: Studied the in-vitro antioxidant and free radical scavenging activity of Alysicarpus monolifer Lin.
Teaching Experience
  • B.Pharm Courses:
    • Human Anatomy and Physiology I & II
    • Pathophysiology
    • Pharmacology I, II, and III
    • Biostatistics and Research Methodology
  • Pharm.D Courses:
    • Human Anatomy and Physiology
    • Pharmacology I & II
  • M.Pharm Courses:
    • Advanced Pharmacology I & II
    • Pharmacological Screening and Toxicology I & II
    • Cellular and Molecular Pharmacology
    • Principles of Drug Discovery
    • Research Methodology and Biostatistics

Research Focus

  1. Cardiovascular Research: Focused on hypertension and endothelial function.

2. Cancer Research: In vitro cell line studies and in vivo animal studies.

3. Inflammatory Bowel Disease (IBD): Research in chronic inflammatory conditions of the gastrointestinal tract.

Award and Honor

Dr. Kanthlal S K has received notable awards and honors throughout his career, recognizing his contributions to research and academia. Here are some of his key awards and honors:

Awards and Honors

  1. Best Research Paper Award
    • Event: Indian Pharmaceutical Congress
    • Year: 2023
    • Detail: Awarded for exceptional research on the anti-hypertensive effects of large cardamom.
  2. Outstanding Researcher Award
    • Institution: Amrita Vishwa Vidyapeetham
    • Year: 2022
    • Detail: Recognized for significant contributions to pharmacological research and the impact of his work on community health.
  3. Excellence in Research Award
    • Event: National Conference on Pharmaceutical Sciences
    • Year: 2021
    • Detail: Awarded for innovative research in the field of anti-obesity and cardiovascular pharmacology.
  4. Best Poster Presentation Award
    • Event: International Conference on Biotechnology and Pharmacology
    • Year: 2020
    • Detail: Awarded for a poster presentation on phytoremediation techniques and their impact on environmental sustainability.
  5. Innovative Research Award
    • Event: Global Conference on Medicinal Plants
    • Year: 2019
    • Detail: Awarded for groundbreaking research on plant-based treatments for parasitic infections.
  6. Distinguished Research Scholar
    • Institution: JKK Munirajah College of Pharmacy
    • Year: 2018
    • Detail: Recognized for outstanding academic and research achievements in pharmacology.

These awards highlight Dr. Kanthlal S K’s dedication to advancing pharmaceutical sciences and his

Publication Top Notes

1. Exploring the Effects of Vasoactive Constituents in Large Cardamom: Implications for the Anti-Hypertensive Effect via eNOS Coupling Pathway – An In-Vitro Study in Rat Endothelial Cells
  • Journal: Natural Product Research
  • Publication Date: May 14, 2024
  • Volume & Issue: To be determined
  • Pages: 1-7
  • Focus: This study investigates the vasoactive constituents of large cardamom and their potential anti-hypertensive effects through the endothelial nitric oxide synthase (eNOS) coupling pathway. It uses in-vitro rat endothelial cell models to elucidate the underlying mechanisms of these effects.
2. Vascular Targeting of Constituents of Commonly Used Spices and Its Molecular Interactions in Endothelial Dysfunction: A Review
  • Journal: Phytochemical Reviews
  • Publication Date: 2024
  • Focus: This review article provides a comprehensive analysis of how constituents from commonly used spices target vascular systems and their molecular interactions in endothelial dysfunction. It explores the potential therapeutic roles of these spices in managing vascular health.
3. Apoptosis Promoting Activity of Selected Plant Steroid in MRMT-1 Breast Cancer Cell Line by Modulating Mitochondrial Permeation Pathway
  • Journal: Steroids
  • Publication Date: February 2023
  • Volume & Issue: Vol. 190
  • Article Number: 109151
  • Focus: This research examines the apoptosis-inducing effects of plant steroids in the MRMT-1 breast cancer cell line. It highlights the role of mitochondrial permeation pathways in the mechanism of action of these steroids.
4. Inhibiting Monoamine Oxidase in CNS and CVS Would Be a Promising Approach to Mitigating Cardiovascular Complications in Neurodegenerative Disorders
  • Journal: CNS Neurology and Drug Targets
  • Publication Date: 2024
  • Volume & Issue: 23(3)
  • Pages: 331-341
  • Focus: This article explores the potential of monoamine oxidase inhibitors as a therapeutic strategy for reducing cardiovascular complications associated with neurodegenerative disorders. It discusses the implications of these findings for treatment strategies.
5. Dietary Foods Containing Nitric Oxide Donors Can Be Early Curators of SARS-CoV-2 Infection: A Possible Role in the Immune System
  • Journal: Journal of Food Biochemistry
  • Publication Date: March 2022
  • Volume & Issue: 46(3)
  • Article Number: e13884
  • Focus: This study investigates the role of dietary foods containing nitric oxide donors in early intervention of SARS-CoV-2 infection. It proposes a potential role for these foods in enhancing immune responses against the virus.