Zu-Chian Chiang | Biochemistry | Best Researcher Award | 13347

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Dr. Zu-Chian Chiang | Biochemistry | Best Researcher Award 

Dr. Zu-Chian Chiang, Fujian Normal University, China

Dr. Zu-Chian Chiang is a postdoctoral fellow at the Biomedical Research Center of Southern China, Fujian Normal University, China, with a rich background in materials and chemical engineering. His research contributions span antibody-drug conjugates (ADCs), functional peptide synthesis, biomaterials for regenerative medicine, and aptamer-based cancer therapy. His work has geographic impact across Taiwan and Mainland China, contributing to translational medicine and oncology through collaborative efforts with prestigious institutions like Academia Sinica and National Taiwan University. His applied research in ADCs and biomaterial scaffolds directly supports cancer treatment innovations. Notable projects include the development of CD47-targeting ADCs for non-small cell lung cancer, and thalidomide-PD1 combinations for enhanced immunotherapy. His publications in Frontiers in Oncology, PLOS ONE, and Current Pharmaceutical Biotechnology highlight his influence in drug delivery and cancer therapeutics. In the vector control domain, his scaffold research contributes to potential localized drug delivery systems. Dr. Chiang has received awards such as the Science and Technology Commissioner honor from Quanzhou and the Biotech Elite Training Award. His achievements exemplify impactful biomedical research with real-world therapeutic implications.

Profile

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🌱 Early Academic Pursuits

Dr. Zu-Chian Chiang embarked on his scientific journey with a passion for chemistry and materials science. He earned his Master’s Degree in Chemistry from Tunghai University, Taiwan (2005–2007), under the guidance of Prof. Feng-Di Lung. Building on this solid foundation, he pursued his Ph.D. in Materials and Chemical Engineering at National United University, Taiwan (2008–2014). During his doctoral studies, he was mentored by Prof. An-Chong Chao and co-advised by Dr. Guo-Chung Dong, focusing on biomaterials and nanomedicine.

Even as a student, Dr. Chiang demonstrated exceptional academic capabilities, earning scholarships and recognition for his innovative research. His academic training laid the groundwork for his future contributions in biomedical engineering and cancer therapeutics.

🧪 Professional Endeavors

Dr. Chiang has held several prestigious postdoctoral positions. His professional journey reflects a commitment to interdisciplinary collaboration and translational research:

  • Postdoctoral Fellow at the Biomedical Research Center of Southern China, Fujian Normal University (2019–Present), working under Prof. Qi Chen.

  • Postdoctoral Fellow at the Institute of Biological Chemistry, Academia Sinica, Taiwan (2016–2019), contributing to the Taiwan Protein Project (TPP) and the Technical Support Platform Spindle Project (TSPA).

  • Postdoctoral Fellow at the Clinical Trial Center, National Taiwan University Hospital (2015–2016), supported by Taiwan’s prestigious Biotech Elite Training Program.

Throughout these roles, Dr. Chiang has engaged in cutting-edge biomedical research with direct implications for drug development and clinical applications.

🔬 Contributions and Research Focus

Dr. Chiang’s research centers on innovative therapeutic materials and drug delivery systems, particularly in cancer therapy. His core interests include:

  • Antibody-Drug Conjugates (ADCs): Targeted cancer therapies such as HER2-positive and CD47-specific ADCs.

  • Functional Peptide Synthesis for bone tissue engineering and cancer inhibition.

  • Bio-Micro-Macro Molecular Materials for regenerative medicine.

  • Aptamer Development as modulators in therapeutic settings.

Notable publications include research on CD47-targeting ADCs (Frontiers in Oncology, 2022) and HER2-positive ADCs (PLOS ONE, 2020). His work on dexamethasone-immobilized chitosan scaffolds and chitosan-caffeic acid hybrids also provides valuable insights into localized drug delivery and tissue engineering.

🏆 Accolades and Recognition

Dr. Chiang’s dedication has been acknowledged through numerous awards:

  • 🥇 Science and Technology Commissioner, Quanzhou, Fujian Province (2020)

  • 🥇 Biotech Elite Training Award, National Taiwan University & Ministry of Science and Technology (2016)

  • 🥇 Chung Hwa Rotary Doctoral Program Award, Taiwan (2012)

  • 🥇 Outstanding Doctoral Scholarship, National United University (2010)

  • 🥇 Master’s Program Scholarship, Hunan Fellow Association of Taiwan (2007)

  • 🥇 Rotary Leadership Award, Miaoli Southeastern Xindong Satellite Rotary Club (2017)

These accolades affirm his position as a respected figure in the fields of biomedical chemistry and translational medicine.

🌍 Impact and Influence

Dr. Chiang’s work has made a geographic impact spanning Taiwan and Mainland China. His collaborative research in academia and clinical centers bridges the gap between laboratory research and therapeutic application. He actively contributes as a peer reviewer for the International Journal of Biological Macromolecules, influencing scientific standards and publication quality globally.

He is also engaged in community service through leadership in Rotary International, fostering science-driven community development and education.

🌟 Legacy and Future Contributions

Dr. Chiang’s legacy is being built on the foundation of scientific excellence, mentorship, and translational impact. His research not only pushes the boundaries of biomedical engineering but also aims to enhance the effectiveness of cancer treatments in clinical practice. With a commitment to developing next-generation targeted therapies and biomaterial scaffolds, Dr. Chiang is poised to shape the future of personalized medicine and regenerative technologies.

Looking ahead, he aims to establish interdisciplinary collaborations and contribute to global health initiatives, making life-saving therapies more effective and accessible.

Publication Top Notes

Development of Novel CD47-Specifific ADCs Possessing High Potency Against Non-Small Cell Lung Cancer in vitro and in vivo. 

Author: Z.C., Chiang, Zu Chian, S., Fang, Shubin, Y., Shen, Yangkun, … J., Lin, Jizhen, Q., Chen, Qi

Journal: Frontiers in Oncology,

Year: 2022

Preparation and characterization of dexamethasone-immobilized chitosan scaffold

Author: Z.C., Chiang, Zu Chian, S., Yu, Shuhuei, A., Chao, Anchong, G.C., Dong, Guo Chung

Journal: Journal of Bioscience and Bioengineering, 

Year: 2012

 

Sumit Kumar Singh | Biochemistry | Life Sciences Innovation Award

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Sumit Kumar Singh | Biochemistry | Life Sciences Innovation Award

Dr. Sumit Kumar Singh, Amity University, India

Dr. Sumit Kumar Singh is a researcher in Biotechnology at Amity University, India. He holds a Ph.D. in Biotechnology (2024) and has extensive research experience, including over a decade as a Senior Research Fellow at ICAR-IARI, Pusa. His work focuses on wheat genetics, molecular marker-assisted breeding, and food quality improvement. Dr. Singh has published extensively in high-impact journals and has qualified GATE in Biotechnology multiple times. His research contributes to developing wheat varieties with improved nutritional and processing traits, particularly for celiac disease mitigation.

Profile

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Early Academic Pursuits 🎓

Dr. Sumit Kumar Singh’s academic journey is a testament to his unwavering dedication to the field of biotechnology. Born on September 24, 1987, he exhibited an early interest in the sciences. His foundational education was rooted in the West Bengal education system, where he completed his 10th and 12th from W.B.B.S.E and W.B.C.H.S.E, respectively. His keen interest in life sciences and biotechnology led him to pursue a B.Sc. in Biotechnology (Hons.) from the University of Burdwan at D.I.S.T Durgapur, where he laid the groundwork for his future research endeavors.

Furthering his passion, he completed an M.Sc. in Biotechnology from Jiwaji University at B.C.P.S Gwalior in 2010, where he deepened his understanding of molecular biology and genetic engineering. His academic thirst culminated in a Ph.D. in Biotechnology from Amity University in 2024, where his research focused on developing durum wheat lacking major epitopes responsible for celiac disease, a significant contribution to food science and public health.

Professional Endeavors 🌟

Dr. Singh embarked on his professional career with an academic inclination, starting as an Assistant Professor at Boston College, Gwalior (2010-2011). His tenure in academia was short-lived as he transitioned into research, joining the Division of Genetics at ICAR-IARI, Pusa, as a Senior Research Fellow (SRF) in August 2012. This marked the beginning of an extensive and impactful research career.

His ten-year tenure at ICAR-IARI (2014-2024) was instrumental in honing his expertise in wheat genetics and molecular breeding. His contributions spanned multiple research projects, where he focused on marker-assisted breeding, genetic diversity analysis, and physicochemical characterization of wheat varieties. His research helped in the development of improved wheat varieties, particularly targeting the nutritional needs of individuals with gluten intolerance.

Contributions and Research Focus 📚

Dr. Singh’s research has been pivotal in agricultural biotechnology, particularly in wheat genetics. His significant research contributions include:

  • Development of Wheat Lines Free from Celiac Disease Epitopes: His doctoral research focused on eliminating immunogenic epitopes in durum wheat, making it safe for celiac disease patients.
  • Marker-Assisted Breeding (MAB): He played a crucial role in developing near-isogenic wheat lines through MAB, improving grain softness and bread-making quality.
  • Physicochemical and Rheological Trait-Based Analysis: His studies identified Indian wheat varieties suitable for various end-uses, aiding in quality-based wheat classification.
  • Genetic Diversity Studies: His research utilized glutenin protein markers to analyze genetic variations in wheat varieties, supporting sustainable breeding programs.
  • Polyphenol Oxidase (PPO) Activity Studies: He examined the impact of PPO activity on dough color and food quality, contributing to food processing advancements.

His research has been widely recognized in the scientific community, with publications in high-impact journals such as Journal of Cereal Science, Foods, Scientific Reports, and Frontiers in Nutrition.

Accolades and Recognition 🏆

Dr. Singh’s contributions have earned him notable recognition, including:

  • GATE (Biotechnology) Qualification (2011, 2014, 2016): Demonstrating his strong command over the subject.
  • Multiple High-Impact Publications: With over a dozen peer-reviewed research papers, his work has significantly influenced wheat breeding and food biotechnology.
  • Invitations to Conferences and Seminars: He has been an active participant in national and international scientific forums, sharing his findings with the global research community.
  • Collaboration with Esteemed Scientists: He has worked alongside eminent researchers from ICAR-IARI, Amity University, and other premier institutions, contributing to multi-disciplinary projects.

Publication Top Notes

Molecular Marker Assisted Development of Chromosome Aneuploid Lines of Durum Wheat Lacking Gli-A1 or Gli-A2 Loci Harbouring Immunogenic Epitopes for Celiac Disease

Contributors: Sumit K. Singh; A.N. Sahi; Shaily Singhal; Arvind K. Ahlawat; Pranab K. Mandal; Govind Makharia; Anju Mahendru Singh
Journal: Cereal Science

Year: 2025

Physico-Chemical and Rheological Trait-Based Identification of Indian Wheat Varieties Suitable for Different End-Uses

Contributors: Sumit Kumar Singh; Shaily Singhal; Praful Jaiswal; Umer Basu; Anant Narayan Sahi; Anju Mahendru Singh
Journal: Foods

Year: 2024

Analysis of genetic diversity and population structure using glutenin protein markers in various wheat varieties

Contributors: Rai, A.; Singh, S.K.; Singh, S.K.; Sharma, P.; Ahlawat, A.K.; Han, S.S.; Mahendru-Singh, A.
Journal: Plant Genetic Resources: Characterisation and Utilisation
Year: 2023