Prof Dr. Xianfeng Yu | Animal Reproduction | Best Researcher Award
Prof Dr. Xianfeng Yu | Jilin University | China
Prof. Dr. Xian-Feng Yu is a distinguished Professor at the College of Animal Sciences, Jilin University, China, with extensive expertise in animal cloning, stem cell biology, and reproductive biotechnology. He earned his Ph.D. in Animal Science and Technology from Sunchon National University, Korea, and has made groundbreaking contributions, including cloning the world’s first red fluorescent genetically modified cat, high-yielding dairy cows, and the resurrection of a world champion camel. His research focuses on embryonic development, IVF/IVC technologies, and stem cell characterization, with over 35 high-impact publications. Prof. Yu’s pioneering work continues to advance veterinary medicine, biotechnology, and sustainable livestock improvement.
Orcid
Education
Prof. Dr. Xian-Feng Yu began his academic journey with a strong passion for veterinary sciences and animal biotechnology. His early studies provided him with a deep understanding of veterinary medicine, pathology, and clinical applications, laying the groundwork for his future in reproductive and genetic sciences. During his advanced studies, he specialized in animal reproductive physiology and molecular biology, focusing on the characterization of embryonic stem-like cells and gene cloning. His academic pursuits sharpened his expertise in the intricate mechanisms of embryonic development and stem cell behavior, fostering a mindset of innovation and scientific rigor. From the beginning, he demonstrated exceptional dedication to research, which later enabled him to explore and push the frontiers of cloning technology and reproductive biotechnology.
Experience
Prof. Yu’s professional career has been defined by both academic excellence and groundbreaking research endeavors. As a dedicated faculty member at Jilin University, he advanced from a lecturer to a full professor, training young scientists while leading pioneering projects in animal biotechnology. He also gained valuable global exposure as a visiting scholar and postdoctoral researcher at esteemed institutions, where he collaborated with leading experts in reproductive biology and biotechnology. Beyond academia, he played a crucial role in biotechnology centers abroad, spearheading projects involving animal cloning and embryo research. These diverse experiences enriched his scientific outlook and allowed him to build bridges between academia, applied science, and industrial biotechnology, strengthening his global presence as a research leader.
Research Focus
Prof. Yu’s research contributions have been pivotal in the field of animal cloning and reproductive biotechnology. His expertise spans animal cloning, in vitro fertilization and embryo culture, embryonic stem cell isolation, and molecular characterization of pluripotency genes. Among his most notable achievements is the cloning of a world champion camel, resurrected from decade-old preserved tissues, which gained global attention for its scientific and cultural significance. He also pioneered the cloning of the world’s first red fluorescent genetically modified cat, a breakthrough in transgenic animal research. Additionally, he contributed to the cloning of high-yielding dairy cows, which holds transformative potential for sustainable livestock industries. His work consistently combines molecular genetics, embryology, and biotechnology to address practical challenges in agriculture and veterinary medicine while also opening new doors in genetic engineering and conservation biology.
Accolades and Recognition
Prof. Yu’s exceptional body of work has earned him recognition both nationally and internationally. His scientific achievements, particularly in animal cloning and genetic modification, are widely cited and celebrated as breakthroughs that showcase the possibilities of modern biotechnology. By publishing extensively in high-impact journals across disciplines like reproductive biology, genetics, and molecular development, he has cemented his reputation as a thought leader. His collaborations with world-renowned scientists and contributions to high-profile projects highlight his standing in the global research community. Furthermore, his ability to translate complex scientific principles into practical applications has brought him professional acclaim and the trust of peers, institutions, and industry stakeholders.
Impact and Influence
The impact of Prof. Yu’s research extends far beyond academic circles. His pioneering work has provided transformative tools for animal breeding, livestock improvement, and the conservation of endangered species. The cloning of high-yielding dairy cows demonstrates his role in enhancing food security, while his work with camels has both economic and cultural resonance in regions that rely on these animals. His research on embryonic stem cells and transgenic animals also contributes to advancing biomedical sciences, with potential applications in regenerative medicine and genetic therapies. Moreover, as an educator and mentor, he has shaped the next generation of researchers, ensuring that his knowledge and expertise continue to influence the scientific community for years to come.
Publications
ER Stress Disrupts MFN2-Related Mitophagy via HRD1-PINK1/ Parkin Axis in Bovine Embryos.
Authors: Shu-Ming Shi; Li-Ying Liu; Zhi-Chao Chi; Lin-Yi Qu; Jing-Hang Li; Guan-Lin Jia; Yu-Yan He; Yong-Xun Jin; Ming-Jun Zhang; Xian-Feng Yu
Journal: Theriogenology
Year: 2025
Galangin Regulates Oxidative Stress Levels in Porcine Embryos Through Interaction with the Neh1 Domain of Nrf2.
Authors: Zhi-Chao Chi; Shu-Ming Shi; Li-Ying Liu; Lin-Yi Qu; Jing-Hang Li; Guan-Lin Jia; Yu-Yan He; Lin-Xuan Li; Yong-Xun Jin; Ming-Jun Zhang et al.
Journal: Antioxidants
Year: 2025
Salidroside Supplementation Affects In Vitro Maturation and Preimplantation Embryonic Development by Promoting Meiotic Resumption.
Authors: Shuming Shi; Zhaojun Geng; Xianfeng Yu; Bing Hu; Liying Liu; Zhichao Chi; Linyi Qu; Mingjun Zhang; Yongxun Jin
Journal: Genes
Year: 2023
Hydroxyurea affects in vitro porcine oocyte maturation through increased apoptosis and oxidative stress.
Authors: Wei Gao; Yongxun Jin; Jindong Hao; Siyi Huang; Dongxu Wang; Fushi Quan; Mingjun Zhang; Jiabao Zhang; Wenzhi Ren; Xianfeng Yu
Journal: Bioscience Reports
Year: 2021
Conclusion
Prof. Dr. Xian-Feng Yu stands as a pioneering figure whose career has seamlessly integrated academic rigor, innovative research, and global collaboration. From his early academic dedication to his transformative achievements in animal cloning and stem cell research, he has consistently pushed the boundaries of reproductive biotechnology. His contributions not only enhance scientific understanding but also create tangible benefits for agriculture, veterinary medicine, and biodiversity conservation. Through his mentorship and international collaborations, he continues to shape the future of biotechnology while inspiring the next generation of researchers. His legacy is one of vision, impact, and enduring commitment to advancing science for the betterment of society.