Dr. Mario Salazar | Productos Naturales | Best Researcher Award
Investigator assistant at Faculty of Biochemical and Pharmaceutical Sciences-UNR/CONICET, Argentina.
Dr. Mario Oscar Salazar is a seasoned researcher and educator in organic chemistry and pharmaceutical sciences, boasting over nineteen years of experience. He obtained his PhD in Chemistry from the National University of Rosario (UNR), Argentina, in 2010, following a Bachelor’s degree in Pharmacy from the same institution. Currently holding the position of Principal Professor of Practice in Pharmacognosy at UNR’s Faculty of Biochemical and Pharmaceutical Sciences, he also serves as an Adjunct Researcher at CONICET (National Scientific and Technical Research Council). Dr. Salazar’s research focuses on the chemical modification of natural products, enzyme inhibition, and effect-directed analysis, employing advanced analytical techniques such as NMR spectroscopy, HPLC-UV, GC-MS, and HPLC-HRMS. His contributions are reflected in numerous publications and collaborations with national and international research groups, aiming to explore the therapeutic potential of natural compounds and develop innovative pharmaceutical solutions. His leadership and expertise continue to drive advancements in organic chemistry and pharmaceutical sciences.
Education
Dr. Mario Oscar Salazar pursued his academic journey at the National University of Rosario (UNR), Argentina, where he obtained his PhD in Chemistry from April 2006 to March 2010. Prior to this, he completed his Bachelor of Pharmacy degree at the same institution between April 1999 and May 2005. These educational achievements laid the groundwork for his distinguished career in organic chemistry research, during which he has made significant contributions to the field through extensive publications, research projects, and academic appointments. His academic qualifications reflect a deep commitment to advancing knowledge in chemistry and pharmaceutical sciences, particularly in the realm of natural product chemistry and enzyme inhibition research.
Professional Experience
Dr. Mario Oscar Salazar has amassed a wealth of professional experience, primarily centered around his roles in research, academia, and consultancy. Since October 2018, he has served as the Principal Professor of Practice in Pharmacognosy at the Faculty of Biochemical and Pharmaceutical Sciences of the National University of Rosario (UNR), where he continues to impart his expertise to students. Concurrently, since November 2016, he has held the position of Adjunct Researcher at CONICET, further solidifying his commitment to advancing scientific inquiry. Previously, he served as an Assistant Researcher at CONICET from April 2012 to October 2016, and as a Post-Doctoral Researcher at the Rosario Chemistry Institute (CONICET-UNR) from April 2010 to March 2012. His extensive tenure as a Teaching Assistant in Pharmacognosy at UNR from May 2005 to September 2018 underscores his dedication to both research and education in the field of organic chemistry and pharmaceutical sciences.
Research Interest
Dr. Mario Oscar Salazar’s research interests are deeply rooted in organic chemistry, particularly focusing on the chemistry of natural products and enzyme inhibition. His work spans various aspects of chemical modification of natural extracts, including sulfonylation, halogenations, and thiocyanation, aimed at altering their molecular diversity and enhancing biological activities. He is particularly adept in employing analytical techniques such as NMR spectroscopy, HPLC-UV, GC-MS, and HPLC-HRMS for the characterization and analysis of complex mixtures. Dr. Salazar’s research also extends to effect-directed analysis and the development of innovative methods for the identification and evaluation of bioactive compounds. His contributions significantly advance the understanding and application of organic chemistry in pharmaceutical development and environmental science.
Award and Honors
Dr. Mario Oscar Salazar has garnered notable recognition and honors throughout his career for his contributions to the field of organic chemistry and pharmaceutical sciences. His achievements include being awarded the prestigious position of Principal Professor of Practice in Pharmacognosy at the Faculty of Biochemical and Pharmaceutical Sciences of the National University of Rosario (UNR). Additionally, his research has been widely acknowledged through numerous publications in high-impact journals and presentations at international conferences. Dr. Salazar’s scholarly work has earned him a respectable citation index and an h-index of 14, reflecting the significance and influence of his research contributions in the scientific community.
Research Skills
Dr. Mario Oscar Salazar is a highly skilled researcher with a broad range of expertise in organic chemistry and pharmaceutical sciences. His research skills are exemplified through proficiency in various analytical techniques essential for characterizing complex mixtures and bioactive compounds, including NMR spectroscopy, HPLC-UV, GC-MS, IR spectroscopy, and HPLC-HRMS. His specialization in chemical modification reactions such as sulfonylation, halogenations, and thiocyanation has significantly contributed to altering the molecular diversity and enhancing the biological activities of natural products. Dr. Salazar’s research also extends to studying enzyme inhibition mechanisms, particularly focusing on Ī±-glucosidase and Ī²-glucosidase inhibitors. He is adept at effect-directed analysis methods for identifying bioactive compounds and has a strong publication record in high-impact journals, alongside frequent presentations at international conferences. Collaborative by nature, Dr. Salazar has successfully partnered with prestigious institutions like CONICET and various research institutes, underscoring his commitment to advancing scientific knowledge and innovation in his field.
Publications
- Chemically engineered extracts: source of bioactive compounds
- Authors: IA Ramallo, MO Salazar, L Mendez, RLE Furlan
- Year: 2011
- Citations: 85
- Journal: Accounts of chemical research 44 (4), 241-250
- Modified Ī²-Cyclodextrin Inclusion Complex to Improve the Physicochemical Properties of Albendazole. Complete In Vitro Evaluation and Characterization
- Authors: A Garcia, D Leonardi, MO Salazar, MC Lamas
- Year: 2014
- Citations: 74
- Journal: PloS one 9 (2), e88234
- A rapid TLC autographic method for the detection of glucosidase inhibitors
- Authors: MO Salazar, RLE Furlan
- Year: 2007
- Citations: 73
- Journal: Phytochemical Analysis: An International Journal of Plant Chemical and …
- Unsaturated long chain free fatty acids are input signals of the Salmonella enterica PhoP/PhoQ regulatory system
- Authors: G Viarengo, MI Sciara, MO Salazar, PM Kieffer, RLE FurlƔn, EG VƩscovi
- Year: 2013
- Citations: 48
- Journal: Journal of Biological Chemistry 288 (31), 22346-22358
- Brominated extracts as source of bioactive compounds
- Authors: L MĆ©ndez, MO Salazar, IA Ramallo, RLE Furlan
- Year: 2011
- Citations: 35
- Journal: ACS combinatorial science 13 (2), 200-204
- Discovery of a Ī²-glucosidase inhibitor from a chemically engineered extract prepared through sulfonylation
- Authors: MO Salazar, O Micheloni, AM Escalante, RLE Furlan
- Year: 2011
- Citations: 31
- Journal: Molecular diversity 15 (3), 713-719
- Metabolic Footprinting of a Clear Cell Renal Cell Carcinoma in Vitro Model for Human Kidney Cancer Detection
- Authors: ME Knott, M Manzi, N Zabalegui, MO Salazar, LI Puricelli, ME Monge
- Year: 2018
- Citations: 29
- Journal: Journal of proteome research 17 (11), 3877-3888
- Thin layer chromatographyāautographyāhigh resolution mass spectrometry analysis: accelerating the identification of acetylcholinesterase inhibitors
- Authors: IA Ramallo, MO Salazar, RLE Furlan
- Year: 2015
- Citations: 28
- Journal: Phytochemical analysis 26 (6), 404-412
- Chemically engineered extracts: Bioactivity alteration through sulfonylation
- Authors: MO Salazar, IA Ramallo, O Micheloni, MG Sierra, RLE Furlan
- Year: 2009
- Citations: 28
- Journal: Bioorganic & medicinal chemistry letters 19 (17), 5067-5070
- Effect-directed analysis in food by thin-layer chromatography assays
- Authors: I Cabezudo, MO Salazar, IA Ramallo, RLE Furlan
- Year: 2022
- Citations: 26
- Journal: Food Chemistry, 132937